biostudies-literatureLuo JNational Natural Science Foundation of China (National Science Foundation of China)3243-3248https://www.ebi.ac.uk/biostudies/studies/S-EPMC12669774biostudies-literatureUnknown39(18)<h4>Aims</h4>To investigate the ocular symptoms and characteristics exhibited by extranodal NK/T-cell lymphoma (ENKTL) patients.<h4>Methods</h4>One hundred sixty-eight patients with mature T/Natural Killer-cell Lymphoma (MTNKL) were recruited in this study, among whom 107 cases were ENKTL patients. A retrospective analysis was conducted on 12 of these ENKTL patients who had ocular symptoms. Results of ophthalmic and systemic auxiliary examinations, disease progression, and prognosis were documented.<h4>Results</h4>Ocular symptoms occurred in bilateral eyes (n = 4) and unilateral eyes (n = 8). The average interval from the diagnosis of ENKTL to the onset of ocular symptoms was 18.1 (±20.8) months. According to the ocular symptoms and auxiliary examinations, eight patients had ocular adnexalEye (London, England)Ocular manifestations of patients with extranodal NK/T-cell lymphoma.PMC1266977481770963Liu CXLi JFei PMa YJLuo JZhao PQTao RGu VYfalseOcular manifestations of patients with extranodal NK/T-cell lymphoma.<h4>Aims</h4>To investigate the ocular symptoms and characteristics exhibited by extranodal NK/T-cell lymphoma (ENKTL) patients.<h4>Methods</h4>One hundred sixty-eight patients with mature T/Natural Killer-cell Lymphoma (MTNKL) were recruited in this study, among whom 107 cases were ENKTL patients. A retrospective analysis was conducted on 12 of these ENKTL patients who had ocular symptoms. Results of ophthalmic and systemic auxiliary examinations, disease progression, and prognosis were documented.<h4>Results</h4>Ocular symptoms occurred in bilateral eyes (n = 4) and unilateral eyes (n = 8). The average interval from the diagnosis of ENKTL to the onset of ocular symptoms was 18.1 (±20.8) months. According to the ocular symptoms and auxiliary examinations, eight patients had ocular adnexal2025-01-01T00:00:00Z2025 Dec2026-06-06T07:11:33.675Z2026-06-06T03:06:28.418ZS-EPMC126697744105771410.1038/s41433-025-04052-1