biostudies-literatureUnknownBaek GStudy DesignRetrospective Cohort Study.ObjectivesThere are several approaches for lumbar fusion, which is often used to treat degenerative lumbar spondylolisthesis. This study aimed to compare perioperative complications, mortality, discharge disposition, and costs amongst patients undergoing anterior (ALIF) and posterior/transforaminal lumbar interbody fusion (P/TLIF).MethodsThe National Inpatient Sample was queried from 2016-2022 for admissions after ALIF, PLIF, or TLIF in the setting of degenerative lumbar spondylolisthesis. Perioperative complications, discharge disposition, and mortality rates were compared using survey-weighted regression models. Cost and length of stay (LOS) were compared using survey-weighted means and t-tests. Significance was set at <i>P</i> < 0.05.Results70,580 Global spine journal21925682251404891https://www.ebi.ac.uk/biostudies/studies/S-EPMC12672284biostudies-literatureALIF Versus P/TLIF for Lumbar Spondylolisthesis: National Outcomes on Complications, Disposition, Mortality, and Cost From 2016 to 2022.PMC12672284Dalton JFano AHilibrand ASSchroeder GDAlvarez APGiakas AVaccaro ARKepler CKBaek GMastrokostas LERazi AEFassett DRKurd MFMastrokostas PGLee YSingh RNg MKfalseALIF Versus P/TLIF for Lumbar Spondylolisthesis: National Outcomes on Complications, Disposition, Mortality, and Cost From 2016 to 2022.Study DesignRetrospective Cohort Study.ObjectivesThere are several approaches for lumbar fusion, which is often used to treat degenerative lumbar spondylolisthesis. This study aimed to compare perioperative complications, mortality, discharge disposition, and costs amongst patients undergoing anterior (ALIF) and posterior/transforaminal lumbar interbody fusion (P/TLIF).MethodsThe National Inpatient Sample was queried from 2016-2022 for admissions after ALIF, PLIF, or TLIF in the setting of degenerative lumbar spondylolisthesis. Perioperative complications, discharge disposition, and mortality rates were compared using survey-weighted regression models. Cost and length of stay (LOS) were compared using survey-weighted means and t-tests. Significance was set at <i>P</i> < 0.05.Results70,580 2025-01-01T00:00:00Z2025 Dec2026-06-05T22:15:27.039Z2026-05-22T03:15:52.048ZS-EPMC126722844133008510.1177/21925682251404891