{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Liu Y"],"funding":["Natural Science Foundation of Ningxia Province","National Key R&amp;D Program of Ningxia Hui Autonomous Region of China","National Natural Science Foundation of China"],"pagination":["2418516"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12674345"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["35(1)"],"pubmed_abstract":["This study investigates whether <i>Bacillus pumilus</i> TS1 improves growth performance and alleviates inflammatory damage in broilers and explored its feasibility as an antibiotic alternative. We divided 240 one-day-old AA308 white-finned broilers into five groups (con, LPS, TS1L + LPS, TS1M + LPS and TS1H + LPS). The TS1L + LPS, TS1M + LPS and TS1H + LPS groups were fed TS1 for 15 days by gavage. The LPS, TS1L + LPS, TS1M + LPS and TS1H + LPS groups were injected intraperitoneally with 1 mg/kg LPS for three days. We investigated the probiotic and anti-inflammatory activities by measuring body weight, sequencing the intestinal flora and examining the structure of tissues by using pathological stain, real-time PCR, Western blotting and immunohistochemical detection. TS1 could improve growt"],"journal":["Animal biotechnology"],"pubmed_title":["Anti-inflammatory properties of &lt;i&gt;Bacillus pumilus&lt;/i&gt; TS1 in lipopolysaccharide-induced inflammatory damage in broilers."],"pmcid":["PMC12674345"],"funding_grant_id":["31602027","2023AAC05052","21BEF02019"],"pubmed_authors":["Wan S","Liu Y","Li H","Li Z","Tang S","Liu S"],"additional_accession":[]},"is_claimable":false,"name":"Anti-inflammatory properties of &lt;i&gt;Bacillus pumilus&lt;/i&gt; TS1 in lipopolysaccharide-induced inflammatory damage in broilers.","description":"This study investigates whether <i>Bacillus pumilus</i> TS1 improves growth performance and alleviates inflammatory damage in broilers and explored its feasibility as an antibiotic alternative. We divided 240 one-day-old AA308 white-finned broilers into five groups (con, LPS, TS1L + LPS, TS1M + LPS and TS1H + LPS). The TS1L + LPS, TS1M + LPS and TS1H + LPS groups were fed TS1 for 15 days by gavage. The LPS, TS1L + LPS, TS1M + LPS and TS1H + LPS groups were injected intraperitoneally with 1 mg/kg LPS for three days. We investigated the probiotic and anti-inflammatory activities by measuring body weight, sequencing the intestinal flora and examining the structure of tissues by using pathological stain, real-time PCR, Western blotting and immunohistochemical detection. TS1 could improve growt","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Nov","modification":"2026-06-06T00:06:06.72Z","creation":"2026-05-23T03:13:44.259Z"},"accession":"S-EPMC12674345","cross_references":{"pubmed":["39460459"],"doi":["10.1080/10495398.2024.2418516"]}}