{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["20(12)"],"submitter":["Saunders N"],"pubmed_abstract":["<h4>Background</h4>The marked heterogeneity of Amyotrophic Lateral Sclerosis (ALS) combined with a lack of biomarkers are key contributing factors to the lack of disease-modifying treatments. The Comprehensive Analysis Platform to Understand Remedy and Eliminate ALS (CAPTURE ALS) is a Canadian platform designed to create the most comprehensive picture of people living with ALS with the objective of facilitating ALS research initiatives worldwide.<h4>Objectives</h4>The main aims of CAPTURE ALS include: (1) to characterize ALS and healthy controls with biosamples and data in order to provide the most comprehensive picture of individuals living with ALS to date; (2) to create a de-identified database and biosample repository linked to detailed clinical information; and (3) to develop and impl"],"journal":["PloS one"],"pagination":["e0332430"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12677780"],"repository":["biostudies-literature"],"pubmed_title":["Comprehensive analysis platform to understand, remedy, and eliminate amyotrophic lateral sclerosis (CAPTURE ALS): Study protocol for a Canadian multicenter, multimodal, longitudinal observational study."],"pmcid":["PMC12677780"],"pubmed_authors":["Abrahao A","Medina YI","Luth W","Tremblay-Desbiens C","Magnussen C","Das S","Matte G","Saunders N","Abou-Haidar R","Genuis SK","Kriz J","Kang H","Taylor D","Yunusova Y","Bubela T","Genge A","Zinman L","Bowser R","Johnston WS","Jones KE","Karamchandani J","Velde CV","Blais M","Ferry N","Evans A","Rogaeva E","Dhanoa A","Bouvier L","Graham SJ","Pfeffer G","Boivin MN","Anand T","Seres P","Tam F","Dupre N","Frater Y","Kalra S","Chiappini J","Robertson J","Bhinder H","Greiner R"],"additional_accession":[]},"is_claimable":false,"name":"Comprehensive analysis platform to understand, remedy, and eliminate amyotrophic lateral sclerosis (CAPTURE ALS): Study protocol for a Canadian multicenter, multimodal, longitudinal observational study.","description":"<h4>Background</h4>The marked heterogeneity of Amyotrophic Lateral Sclerosis (ALS) combined with a lack of biomarkers are key contributing factors to the lack of disease-modifying treatments. The Comprehensive Analysis Platform to Understand Remedy and Eliminate ALS (CAPTURE ALS) is a Canadian platform designed to create the most comprehensive picture of people living with ALS with the objective of facilitating ALS research initiatives worldwide.<h4>Objectives</h4>The main aims of CAPTURE ALS include: (1) to characterize ALS and healthy controls with biosamples and data in order to provide the most comprehensive picture of individuals living with ALS to date; (2) to create a de-identified database and biosample repository linked to detailed clinical information; and (3) to develop and impl","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025","modification":"2026-06-05T23:19:47.465Z","creation":"2026-05-23T03:13:55.254Z"},"accession":"S-EPMC12677780","cross_references":{"pubmed":["41343582"],"doi":["10.1371/journal.pone.0332430"]}}