{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["5(6)"],"submitter":["Guarducci MA"],"pubmed_abstract":["A novel copper-(I)-anchored covalent organic polymer (Cu<sup>+</sup>@COP) is presented as a robust, heterogeneous catalyst for copper-catalyzed azide-alkyne cycloaddition (CuAAC), operating without the need for external reducing agents or observable copper leaching. Cu<sup>+</sup> stabilization is achieved via multidentate N,O-ligand coordination within the polymer matrix, enabling high catalytic efficiency (up to 95% yield) and recyclability. Structural, spectroscopic, and ICP-OES analyses confirm Cu presence, offering an alternative to traditional CuAAC protocols. This system combines operational simplicity, reduced waste, and green chemistry principles, positioning Cu<sup>+</sup>@COP as a practical catalyst for applications in synthetic and materials chemistry."],"journal":["ACS organic & inorganic Au"],"pagination":["507-517"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12679302"],"repository":["biostudies-literature"],"pubmed_title":["Copper(I)-Anchoring Covalent Organic Polymer for Heterogeneous CuAAC Reaction without Reducing Agents and Copper Leaching."],"pmcid":["PMC12679302"],"pubmed_authors":["Manetto S","Guarducci MA","Villani C","Amato F","Fontana A","Pilato S","Ciogli A","Coluccia M","Marrani AG","Guglielmi P","Mazzoccanti G"],"additional_accession":[]},"is_claimable":false,"name":"Copper(I)-Anchoring Covalent Organic Polymer for Heterogeneous CuAAC Reaction without Reducing Agents and Copper Leaching.","description":"A novel copper-(I)-anchored covalent organic polymer (Cu<sup>+</sup>@COP) is presented as a robust, heterogeneous catalyst for copper-catalyzed azide-alkyne cycloaddition (CuAAC), operating without the need for external reducing agents or observable copper leaching. Cu<sup>+</sup> stabilization is achieved via multidentate N,O-ligand coordination within the polymer matrix, enabling high catalytic efficiency (up to 95% yield) and recyclability. Structural, spectroscopic, and ICP-OES analyses confirm Cu presence, offering an alternative to traditional CuAAC protocols. This system combines operational simplicity, reduced waste, and green chemistry principles, positioning Cu<sup>+</sup>@COP as a practical catalyst for applications in synthetic and materials chemistry.","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Dec","modification":"2026-06-05T23:27:20.599Z","creation":"2026-05-23T03:13:32.905Z"},"accession":"S-EPMC12679302","cross_references":{"pubmed":["41356445"],"doi":["10.1021/acsorginorgau.5c00067"]}}