biostudies-literatureKou JThe Postdoctoral Fellowship Program of CPSFThe Collaborative Research Agreement between West China Hospital, Sichuan University and Chengdu Huashi Micro-Professional Vision Technology Company Limited, Shenzhen Thondar Technology Corporation1882-1893https://www.ebi.ac.uk/biostudies/studies/S-EPMC12682103biostudies-literatureUnknown45(7)<h4>Purpose</h4>To assess second-year myopia progression in children after a 1-year randomised controlled trial of individualised ocular refraction customisation (IORC) spectacle lenses, customised to each eye's peripheral refraction.<h4>Methods</h4>A total of 161 children were randomised to wear IORC lenses with high (+4.50 D, IORC-H), medium (+3.50 D, IORC-M) or low (+2.50 D, IORC-L) myopic defocus or single-vision lenses (SV). In year 2, all children received IORC-H, forming the IORC-H1/H2/H3/H4 groups, respectively. An external SV (eSV, n = 42) group was matched to year 2 baseline parameters. Spherical equivalent refraction (SER) and axial length (AL) were measured every 6 months.<h4>Results</h4>Compared with the eSV group (12-month mean [SD] changes: SER -0.56 [0.44] D, AL 0.32 [0.16]Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)Myopia control efficacy of individualised ocular refraction customisation spectacle lenses: A 2-year follow-up study.PMC12682103GZC20231794HX-H2112325Xiong LLiu LChen XLei SKou JWu YfalseMyopia control efficacy of individualised ocular refraction customisation spectacle lenses: A 2-year follow-up study.<h4>Purpose</h4>To assess second-year myopia progression in children after a 1-year randomised controlled trial of individualised ocular refraction customisation (IORC) spectacle lenses, customised to each eye's peripheral refraction.<h4>Methods</h4>A total of 161 children were randomised to wear IORC lenses with high (+4.50 D, IORC-H), medium (+3.50 D, IORC-M) or low (+2.50 D, IORC-L) myopic defocus or single-vision lenses (SV). In year 2, all children received IORC-H, forming the IORC-H1/H2/H3/H4 groups, respectively. An external SV (eSV, n = 42) group was matched to year 2 baseline parameters. Spherical equivalent refraction (SER) and axial length (AL) were measured every 6 months.<h4>Results</h4>Compared with the eSV group (12-month mean [SD] changes: SER -0.56 [0.44] D, AL 0.32 [0.16]2025-01-01T00:00:00Z2025 Nov2026-06-07T04:46:05.331Z2026-06-07T03:06:49.978ZS-EPMC126821034078808410.1111/opo.70002