biostudies-literatureUnknown34Jagadeesan J<h4>Objective</h4>To accurately provide real-time intraoperative guidance on margins despite significant lung deformation. With lung cancer screening programs, smaller, early-stage lung nodules are being detected. Sublobar resection of peripheral small nodules is noinferior to lobar resection in terms of disease-free recurrence and long-term survival while preserving healthy lung function. However, accurately ensuring sufficient resection margin is challenging.<h4>Methods</h4>A novel navigation system with a tumor marker (J-bar), surgical stapler instrumented with a position sensor, and software to compute the distances in real time has been developed and utilized during surgery to resect lung cancer. The software measurement of the J-bar to the tip of the stapler cutline (J-bar-tip) was cJTCVS techniques207-218https://www.ebi.ac.uk/biostudies/studies/S-EPMC12682956biostudies-literatureReal-time margin assessment for video-assisted thoracic surgery: A pilot clinical trial.PMC12682956Sholl LMBueno RBarlow JJaklitsch MTJagadeesan JSadek ASchmidlin EJMukherjee RLobo SAlam ZSLucas ASwanson SJfalseReal-time margin assessment for video-assisted thoracic surgery: A pilot clinical trial.<h4>Objective</h4>To accurately provide real-time intraoperative guidance on margins despite significant lung deformation. With lung cancer screening programs, smaller, early-stage lung nodules are being detected. Sublobar resection of peripheral small nodules is noinferior to lobar resection in terms of disease-free recurrence and long-term survival while preserving healthy lung function. However, accurately ensuring sufficient resection margin is challenging.<h4>Methods</h4>A novel navigation system with a tumor marker (J-bar), surgical stapler instrumented with a position sensor, and software to compute the distances in real time has been developed and utilized during surgery to resect lung cancer. The software measurement of the J-bar to the tip of the stapler cutline (J-bar-tip) was c2025-01-01T00:00:00Z2025 Dec2026-07-01T03:19:51.739Z2026-07-01T03:08:00.677ZS-EPMC126829564136837110.1016/j.xjtc.2025.08.015