{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["34"],"submitter":["Cano JR"],"pubmed_abstract":["<h4>Objective</h4>To assess the technical feasibility and surgical safety of dynamic, 3-dimensional (3D) customized prostheses for complex chest wall reconstruction across a multicenter experience.<h4>Methods</h4>We conducted a retrospective, descriptive observational study involving 51 patients from 5 hospitals in Spain who underwent chest wall reconstruction via a custom-designed, spring-like 3D-printed titanium implants between 2016 and 2023. Data collected included surgical indication (oncologic, traumatic, or infectious), patient demographics, prosthesis type, operative time, hospital stay, complications, and follow-up outcomes.<h4>Results</h4>Indications included 35 oncologic, 11 traumatic, 3 infectious, and 2 functional cases (winged scapula). A total of 51 prostheses were implanted, including bilateral and unilateral sternocostal, costal, costovertebral, sternoclavicular, and scapulothoracic reconstructions. The mean operative time was 270 minutes (range, 75-720 minutes), and median follow-up was 2.5 years (range, 3 months to 8 years). Four minor complications were recorded, none requiring implant removal. No cases of prosthesis failure occurred independently of patient death.<h4>Conclusions</h4>Dynamic 3D-customized prostheses provide a structurally stable yet flexible alternative to conventional rigid implants for chest wall reconstruction. Their spring-like geometry allows anatomical adaptation and facilitates intraoperative placement, contributing to safe and reproducible reconstruction in selected cases, with favorable medium-term outcomes. This multicenter experience suggests they may be a feasible and safe option in anatomically complex or functionally demanding thoracic reconstructions."],"journal":["JTCVS techniques"],"pagination":["269-279"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12683048"],"repository":["biostudies-literature"],"pubmed_title":["Custom-made dynamic 3-dimensional-printed prostheses for chest wall reconstruction: A multicenter study."],"pmcid":["PMC12683048"],"pubmed_authors":["Trujillo JC","Lorenzo M","Hernandez-Ferrandez J","Cano JR","Mentado B","Jimenez U","Tavarez W","Monopoli D","Galbis JM","Medina R","Fra-Fernandez S","Munoz-Molina GM","Uribe-Etxebarria N","Moreno-Mata N","Perez D","Leung M","Estors M","Martinez E"],"additional_accession":[]},"is_claimable":false,"name":"Custom-made dynamic 3-dimensional-printed prostheses for chest wall reconstruction: A multicenter study.","description":"<h4>Objective</h4>To assess the technical feasibility and surgical safety of dynamic, 3-dimensional (3D) customized prostheses for complex chest wall reconstruction across a multicenter experience.<h4>Methods</h4>We conducted a retrospective, descriptive observational study involving 51 patients from 5 hospitals in Spain who underwent chest wall reconstruction via a custom-designed, spring-like 3D-printed titanium implants between 2016 and 2023. Data collected included surgical indication (oncologic, traumatic, or infectious), patient demographics, prosthesis type, operative time, hospital stay, complications, and follow-up outcomes.<h4>Results</h4>Indications included 35 oncologic, 11 traumatic, 3 infectious, and 2 functional cases (winged scapula). A total of 51 prostheses were implanted, including bilateral and unilateral sternocostal, costal, costovertebral, sternoclavicular, and scapulothoracic reconstructions. The mean operative time was 270 minutes (range, 75-720 minutes), and median follow-up was 2.5 years (range, 3 months to 8 years). Four minor complications were recorded, none requiring implant removal. No cases of prosthesis failure occurred independently of patient death.<h4>Conclusions</h4>Dynamic 3D-customized prostheses provide a structurally stable yet flexible alternative to conventional rigid implants for chest wall reconstruction. Their spring-like geometry allows anatomical adaptation and facilitates intraoperative placement, contributing to safe and reproducible reconstruction in selected cases, with favorable medium-term outcomes. This multicenter experience suggests they may be a feasible and safe option in anatomically complex or functionally demanding thoracic reconstructions.","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Dec","modification":"2026-05-26T14:03:26.318Z","creation":"2026-05-24T03:12:17.728Z"},"accession":"S-EPMC12683048","cross_references":{"pubmed":["41368406"],"doi":["10.1016/j.xjtc.2025.09.010"]}}