biostudies-literatureMatos LAssociazione Italiana di Oncologia MedicaInstituto de Salud Carlos III104558https://www.ebi.ac.uk/biostudies/studies/S-EPMC12683136biostudies-literatureUnknown84<h4>Background</h4>Routine brain imaging screening (BIS) in patients with metastatic breast cancer (BC) without neurological symptoms is currently not recommended, as no survival/quality-of-life improvements have been demonstrated. We aimed to examine physicians and patients' attitudes and perceptions toward BIS.<h4>Methods</h4>International cross-sectional online survey for patients and physicians, distributed from May 2023 to February 2024. Patients with BC diagnosis were deemed eligible for patients' survey completion and BC-treating physicians were invited to fill the physicians' questionnaire.<h4>Results</h4>A total of 529 physicians from 50 countries (80 % European) responded, mostly medical oncologists (70 %) working in academic hospitals (53 %). Most physicians request BIS (65 %), Breast (Edinburgh, Scotland)Brain imaging screening in metastatic breast cancer: patients' and physicians' perspectives.PMC12683136JR24/00024le Du FMorgan GHaidinger RRodriguez Recio GMuller VCriscitiello CBrucker SLaakmann EMatos LFontes Sousa MSchettini FJerzak KJDieras VLambertini Mvon Kroge PBraga SSchumacher-Wulf ELinn Svan Ramshorst MAgostinetto EfalseBrain imaging screening in metastatic breast cancer: patients' and physicians' perspectives.<h4>Background</h4>Routine brain imaging screening (BIS) in patients with metastatic breast cancer (BC) without neurological symptoms is currently not recommended, as no survival/quality-of-life improvements have been demonstrated. We aimed to examine physicians and patients' attitudes and perceptions toward BIS.<h4>Methods</h4>International cross-sectional online survey for patients and physicians, distributed from May 2023 to February 2024. Patients with BC diagnosis were deemed eligible for patients' survey completion and BC-treating physicians were invited to fill the physicians' questionnaire.<h4>Results</h4>A total of 529 physicians from 50 countries (80 % European) responded, mostly medical oncologists (70 %) working in academic hospitals (53 %). Most physicians request BIS (65 %), 2025-01-01T00:00:00Z2025 Dec2026-06-06T00:16:08.396Z2026-05-23T03:13:58.857ZS-EPMC126831364084922110.1016/j.breast.2025.104558