biostudies-literatureUnknown14(11)Chapain SProstate cancer (PCa) is the second most frequently diagnosed malignancy in men worldwide and a leading cause of cancer-related mortality. The clinical course of PCa is constantly improving, with a trend toward ever greater precision diagnostics and less invasive methods. Magnetic resonance elastography (MRE), a novel modality for quantifying tissue stiffness, significantly enhances detection as a complement to conventional multiparametric magnetic resonance imaging (mpMRI). Providing information about the mechanical properties of prostate tissue, MRE enhances the detection, localization, and characterization of malignant tumors, particularly those that are not optimally visualized with conventional methods. This review covers the underlying principles of MRE, its technological developmentTranslational andrology and urology3771-3781https://www.ebi.ac.uk/biostudies/studies/S-EPMC12683485biostudies-literatureMagnetic resonance elastography for prostate cancer: advancing diagnostic accuracy, tumor characterization, and clinical applications.PMC12683485Yadav DKJin FChen AYang JChapain SWang RRen ZSun SLi QfalseMagnetic resonance elastography for prostate cancer: advancing diagnostic accuracy, tumor characterization, and clinical applications.Prostate cancer (PCa) is the second most frequently diagnosed malignancy in men worldwide and a leading cause of cancer-related mortality. The clinical course of PCa is constantly improving, with a trend toward ever greater precision diagnostics and less invasive methods. Magnetic resonance elastography (MRE), a novel modality for quantifying tissue stiffness, significantly enhances detection as a complement to conventional multiparametric magnetic resonance imaging (mpMRI). Providing information about the mechanical properties of prostate tissue, MRE enhances the detection, localization, and characterization of malignant tumors, particularly those that are not optimally visualized with conventional methods. This review covers the underlying principles of MRE, its technological development2025-01-01T00:00:00Z2025 Nov2026-06-06T00:00:29.267Z2026-05-23T03:13:47.24ZS-EPMC126834854136823710.21037/tau-2025-495