biostudies-literatureMoskowitz JIntramural FDA HHS916-924https://www.ebi.ac.uk/biostudies/studies/S-EPMC12683547biostudies-literatureUnknown2(5)In this work, we evaluate two commercially available portable Raman spectrometers for their ability to accurately determine the presence of ortho-phthalate ester plasticizers, hereafter referred to as phthalates, in poly(vinyl chloride) (PVC) food contact production line tubing. Further, we aim to identify individual plasticizer compounds in the PVC tubing from a panel of multiple components with portable Raman spectroscopy. This is accomplished through library spectral matching of unknown tubing samples with on-instrument library Raman spectra. This library matching methodology functions via the comparison of Raman spectra between unknown food contact tubing samples and a panel of previously scanned, known tubing samples. In both known and unknown tubing, the samples are also analyzed viaACS food science & technologyPortable Raman Spectroscopy for Screening of Phthalate Plasticizers in Food Contact Production Line Tubing and Bottle Cap Gaskets.PMC12683547FD999999Ackerman LKBegley TMoskowitz JYakes BJCarlos KReese KLfalsePortable Raman Spectroscopy for Screening of Phthalate Plasticizers in Food Contact Production Line Tubing and Bottle Cap Gaskets.In this work, we evaluate two commercially available portable Raman spectrometers for their ability to accurately determine the presence of ortho-phthalate ester plasticizers, hereafter referred to as phthalates, in poly(vinyl chloride) (PVC) food contact production line tubing. Further, we aim to identify individual plasticizer compounds in the PVC tubing from a panel of multiple components with portable Raman spectroscopy. This is accomplished through library spectral matching of unknown tubing samples with on-instrument library Raman spectra. This library matching methodology functions via the comparison of Raman spectra between unknown food contact tubing samples and a panel of previously scanned, known tubing samples. In both known and unknown tubing, the samples are also analyzed via2022-01-01T00:00:00Z2022 Apr2026-06-06T14:41:58.334Z2026-06-01T03:06:37.28ZS-EPMC126835474136761310.1021/acsfoodscitech.2c00059