biostudies-literatureUnknown13Li Y<h4>Background</h4>Previous studies have shown that the triglyceride glucose-body mass index (TyG-BMI) is associated with cardiovascular disease, stroke, and cognition. Its relationship with mental health remains underexplored. We aimed to investigate the association between TyG-BMI and mental health in Chinese adults.<h4>Methods</h4>This study utilized data from the China Health and Nutrition Survey (CHNS), an ongoing longitudinal cohort. Participants aged ≥45 years who completed at least two survey rounds between 2009 and 2015 were included. The TyG index was calculated as ln [triglycerides (mg/dL) × fasting blood glucose (mg/dL) / 2]. BMI was calculated as weight (kg) divided by height squared (m²). The TyG-BMI was the product of the TyG index and BMI. Self-rated mental healtFrontiers in public health1672881https://www.ebi.ac.uk/biostudies/studies/S-EPMC12685690biostudies-literatureL-shaped association of triglyceride glucose-body mass index and self-rated mental health among the middle-aged and older adults: a national cohort study in China.PMC12685690Gao QLi YLiu JXu RZhang YZhan HLuo FLi PSu LLin YfalseL-shaped association of triglyceride glucose-body mass index and self-rated mental health among the middle-aged and older adults: a national cohort study in China.<h4>Background</h4>Previous studies have shown that the triglyceride glucose-body mass index (TyG-BMI) is associated with cardiovascular disease, stroke, and cognition. Its relationship with mental health remains underexplored. We aimed to investigate the association between TyG-BMI and mental health in Chinese adults.<h4>Methods</h4>This study utilized data from the China Health and Nutrition Survey (CHNS), an ongoing longitudinal cohort. Participants aged ≥45 years who completed at least two survey rounds between 2009 and 2015 were included. The TyG index was calculated as ln [triglycerides (mg/dL) × fasting blood glucose (mg/dL) / 2]. BMI was calculated as weight (kg) divided by height squared (m²). The TyG-BMI was the product of the TyG index and BMI. Self-rated mental healt2025-01-01T00:00:00Z20252026-06-06T00:17:01.477Z2026-05-23T03:13:59.59ZS-EPMC126856904137771610.3389/fpubh.2025.1672881