biostudies-literatureUnknown14(11)Sadeghi N<h4>Background</h4>Endometrial cancer (EC) is the most common tumour of the female reproductive system, and low-grade EC is the histological type with the best prognosis for its less aggressiveness. Abnormal uterine bleeding is one of the first symptoms that appears and that allows an early diagnosis, while the disease is still confined into the uterus. The objective of this study was to identify risk factors associated with recurrence in low-grade EC across International Federation of Gynaecology and Obstetrics (FIGO) 2009 stages I to IV.<h4>Methods</h4>This is a retrospective study that collected patients surgically treated at the Thames Valley Cancer Centre from March 2010 to January 2020 for low-grade EC. All cases were debated at the multidisciplinary team discussion, both prior to anTranslational cancer research7611-7620https://www.ebi.ac.uk/biostudies/studies/S-EPMC12686162biostudies-literaturePrognostic characteristics and recurrence patterns of grade 1 endometrial carcinoma: a large retrospective analysis of a tertiary center.PMC12686162Sattar ASadeghi NPappa CDamato SDarwish AKehoe SConforti JSmyth SLAddley SZouridis AKashif AFerrari FSoleymani Majd HAbdalla MfalsePrognostic characteristics and recurrence patterns of grade 1 endometrial carcinoma: a large retrospective analysis of a tertiary center.<h4>Background</h4>Endometrial cancer (EC) is the most common tumour of the female reproductive system, and low-grade EC is the histological type with the best prognosis for its less aggressiveness. Abnormal uterine bleeding is one of the first symptoms that appears and that allows an early diagnosis, while the disease is still confined into the uterus. The objective of this study was to identify risk factors associated with recurrence in low-grade EC across International Federation of Gynaecology and Obstetrics (FIGO) 2009 stages I to IV.<h4>Methods</h4>This is a retrospective study that collected patients surgically treated at the Thames Valley Cancer Centre from March 2010 to January 2020 for low-grade EC. All cases were debated at the multidisciplinary team discussion, both prior to an2025-01-01T00:00:00Z2025 Nov2026-06-07T04:58:43.43Z2026-06-07T03:07:34.769ZS-EPMC126861624137803110.21037/tcr-2025-1635