{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Fei X"],"funding":["National Natural Science Foundation of China"],"pagination":["e0150025"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12688083"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["13(10)"],"pubmed_abstract":["As an alternative to the tuberculin skin test (TST) or QuantiFERON-TB Gold In-Tube (QFT-GIT), ESAT6-CFP10 (EC) skin test is an emerging screening method; however, its value in the diagnosis of latent tuberculosis infection (LTBI) in detainees is still unclear in China. Newly admitted detainees meeting inclusion criteria were enrolled, with demographic/clinical data collected via structured questionnaires. TST, EC skin test, and QFT-GIT screenings were performed, documenting the diameter of skin indurations and/or redness at injection sites and blistering reactions at injection sites. In total, 1,038 detainees were enrolled in this study from October 2022 to October 2023 with 236 LTBI (22.7%). The positive rate of TST, EC skin test, and QFT-GIT was 18.1%, 10.6% and 11.9%. The area under the"],"journal":["Microbiology spectrum"],"pubmed_title":["Diagnostic accuracy of the ESAT6-CFP10 skin test for latent tuberculosis infection among jail detainees."],"pmcid":["PMC12688083"],"funding_grant_id":["82574172, 82003516"],"pubmed_authors":["Martinez L","Wang S","Zhu L","Hu X","Tang P","Liu Q","Fei X","Chen C","Wang Z"],"additional_accession":[]},"is_claimable":false,"name":"Diagnostic accuracy of the ESAT6-CFP10 skin test for latent tuberculosis infection among jail detainees.","description":"As an alternative to the tuberculin skin test (TST) or QuantiFERON-TB Gold In-Tube (QFT-GIT), ESAT6-CFP10 (EC) skin test is an emerging screening method; however, its value in the diagnosis of latent tuberculosis infection (LTBI) in detainees is still unclear in China. Newly admitted detainees meeting inclusion criteria were enrolled, with demographic/clinical data collected via structured questionnaires. TST, EC skin test, and QFT-GIT screenings were performed, documenting the diameter of skin indurations and/or redness at injection sites and blistering reactions at injection sites. In total, 1,038 detainees were enrolled in this study from October 2022 to October 2023 with 236 LTBI (22.7%). The positive rate of TST, EC skin test, and QFT-GIT was 18.1%, 10.6% and 11.9%. The area under the","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Oct","modification":"2026-06-05T23:45:14.963Z","creation":"2026-05-23T03:13:42.124Z"},"accession":"S-EPMC12688083","cross_references":{"pubmed":["40960282"],"doi":["10.1128/spectrum.01500-25"]}}