{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["7(6)"],"submitter":["Kricheldorff J"],"pubmed_abstract":["High-frequency deep brain stimulation of the subthalamic nucleus is used to treat motor symptoms in patients with Parkinson's disease. There is evidence that low-frequency stimulation in the range of 4-10 Hz may improve cognitive functions. This study investigates whether low-frequency deep brain stimulation of the subthalamic nucleus in the beta band (20 Hz) frequency can improve response inhibition in patients with Parkinson's disease. In a double-blind crossover design, <i>N</i> = 17 participants with Parkinson's disease performed four neuropsychological experiments, while on their usual dopaminergic medication, under no, standard high-frequency and 20 Hz beta low-frequency deep brain stimulation. The experiments consisted of a response selection task (response execution), a flanker tas"],"journal":["Brain communications"],"pagination":["fcaf474"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12690201"],"repository":["biostudies-literature"],"pubmed_title":["20 Hz beta stimulation of the subthalamic nucleus improves response inhibition in Parkinson's disease."],"pmcid":["PMC12690201"],"pubmed_authors":["Sauer T","Kricheldorff J","Witt K"],"additional_accession":[]},"is_claimable":false,"name":"20 Hz beta stimulation of the subthalamic nucleus improves response inhibition in Parkinson's disease.","description":"High-frequency deep brain stimulation of the subthalamic nucleus is used to treat motor symptoms in patients with Parkinson's disease. There is evidence that low-frequency stimulation in the range of 4-10 Hz may improve cognitive functions. This study investigates whether low-frequency deep brain stimulation of the subthalamic nucleus in the beta band (20 Hz) frequency can improve response inhibition in patients with Parkinson's disease. In a double-blind crossover design, <i>N</i> = 17 participants with Parkinson's disease performed four neuropsychological experiments, while on their usual dopaminergic medication, under no, standard high-frequency and 20 Hz beta low-frequency deep brain stimulation. The experiments consisted of a response selection task (response execution), a flanker tas","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025","modification":"2026-06-06T01:31:10.971Z","creation":"2026-05-24T03:11:14.824Z"},"accession":"S-EPMC12690201","cross_references":{"pubmed":["41383649"],"doi":["10.1093/braincomms/fcaf474"]}}