{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Volkova NA"],"funding":["Ministry of Science and Higher Education of the Russian Federation"],"pagination":["3391"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12691444"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["15(23)"],"pubmed_abstract":["Egg components, including weight of yolk, albumen, and eggshell, are economically important traits in poultry breeding and production, and we thus conducted a genome-wide association study (GWAS) for them. We used an F<sub>2</sub> resource population of hens (<i>n</i> = 142) in different periods of laying, obtained by crossing breeds with contrasting phenotypes, and then genotyped them using the Illumina Chicken 60K iSelect BeadChip. Significant associations were found between 33 single nucleotide polymorphisms (SNPs) and yolk weight at 18-28 weeks of age (YW1). Eighty-seven SNPs were associated with thick albumen weight at 18-28 (TAW1) and 29-42 (TAW2) weeks of age. Four SNPs were associated with eggshell weight at 18-28 weeks of age (ESW1). Fifty-three candidate genes were identified in "],"journal":["Animals : an open access journal from MDPI"],"pubmed_title":["Genome-Wide Egg Hunt: Unhiding Candidate Genes for Egg Component Traits in Layers of an F&lt;sub&gt;2&lt;/sub&gt; Resource Population."],"pmcid":["PMC12691444"],"funding_grant_id":["Theme No. FGGN-2024-0015"],"pubmed_authors":["Griffin DK","Volkova LA","Dzhagaev AY","Volkova NA","Larionova PV","Romanov MN","Sermyagin AA","Zinovieva NA"],"additional_accession":[]},"is_claimable":false,"name":"Genome-Wide Egg Hunt: Unhiding Candidate Genes for Egg Component Traits in Layers of an F&lt;sub&gt;2&lt;/sub&gt; Resource Population.","description":"Egg components, including weight of yolk, albumen, and eggshell, are economically important traits in poultry breeding and production, and we thus conducted a genome-wide association study (GWAS) for them. We used an F<sub>2</sub> resource population of hens (<i>n</i> = 142) in different periods of laying, obtained by crossing breeds with contrasting phenotypes, and then genotyped them using the Illumina Chicken 60K iSelect BeadChip. Significant associations were found between 33 single nucleotide polymorphisms (SNPs) and yolk weight at 18-28 weeks of age (YW1). Eighty-seven SNPs were associated with thick albumen weight at 18-28 (TAW1) and 29-42 (TAW2) weeks of age. Four SNPs were associated with eggshell weight at 18-28 weeks of age (ESW1). Fifty-three candidate genes were identified in ","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Nov","modification":"2026-05-26T11:00:54.966Z","creation":"2026-05-24T03:11:46.84Z"},"accession":"S-EPMC12691444","cross_references":{"pubmed":["41375450"],"doi":["10.3390/ani15233391"]}}