biostudies-literatureLi ZGuangdong Provincial Science and Technology Plan ProjectSpecial fund for scientific innovation strategy-construction of high-level Academy of Agriculture SciencesGuangdong Modern Agro-industry Technology Research SystemCARS-10-Sweetpotato4109https://www.ebi.ac.uk/biostudies/studies/S-EPMC12691887biostudies-literatureUnknown14(23)Despite the nutritional importance of sweetpotato, systematic studies on its lipid metabolism remain largely unexplored. To address this gap, this study investigates the dynamic changes in lipid composition during the development of sweetpotato storage roots using a comprehensive lipidomics approach. Through LC-ESI-MS/MS analysis of 'Guangshu 79' (G79), an orange-fleshed sweetpotato cultivar, across five developmental stages (S1-S5), 612 lipid species were identified, spanning five major classes: glycerolipids (GL, 57.6%), glycerophospholipids (GP, 24.6%), sphingolipids (SP, 13.9%), fatty acids (FA, 3.6%), and prenol lipids (PR, 0.3%). Early developmental phases (S1-S2) were characterized by upregulation of structural phospholipids (PC, PE) and energy-storage triglycerides (TG), supportingFoods (Basel, Switzerland)Lipidomic Profiling of Sweetpotato During Different Developmental Stages Using LC-ESI-MS/MS.PMC126918872024CXTD07R2023PY-JG0082023B1212060038CARS-10-SweetpotatoLiu YLi ZJiang XZhang RWang ZfalseLipidomic Profiling of Sweetpotato During Different Developmental Stages Using LC-ESI-MS/MS.Despite the nutritional importance of sweetpotato, systematic studies on its lipid metabolism remain largely unexplored. To address this gap, this study investigates the dynamic changes in lipid composition during the development of sweetpotato storage roots using a comprehensive lipidomics approach. Through LC-ESI-MS/MS analysis of 'Guangshu 79' (G79), an orange-fleshed sweetpotato cultivar, across five developmental stages (S1-S5), 612 lipid species were identified, spanning five major classes: glycerolipids (GL, 57.6%), glycerophospholipids (GP, 24.6%), sphingolipids (SP, 13.9%), fatty acids (FA, 3.6%), and prenol lipids (PR, 0.3%). Early developmental phases (S1-S2) were characterized by upregulation of structural phospholipids (PC, PE) and energy-storage triglycerides (TG), supporting2025-01-01T00:00:00Z2025 Nov2026-05-26T14:07:27.172Z2026-05-24T03:11:16.809ZS-EPMC126918874137604610.3390/foods14234109