{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Dong Z"],"funding":["Hunan Provincial Natural Science Foundation of China","Yuelushan Laboratory Talent Program","Hunan Province of China Seed Industry Innovation Project"],"pagination":["4056"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12692226"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["14(23)"],"pubmed_abstract":["<i>Lilium lancifolium</i> Thunb., as a predominant variety of medicinal and edible lilies, has long been renowned in traditional medicine for \"moistening the lungs, relieving coughs, and calming the mind to soothe the heart.\" The bitter taste formation in <i>L. lancifolium</i> is predominantly attributed to secondary metabolites such as alkaloids, this study explores an alternative mechanism underlying taste divergence among <i>Lilium brownii</i> var. <i>viridulum</i>, and <i>Lilium pumilum</i> DC, proposing a foundational scientific question: Are peptides one of the important sources of bitterness in <i>Lilium lancifolium</i> Thunb.? Peptidomic analysis identified 8479 peptide sequences, with 46.27% upregulated in <i>L. lancifolium</i> flesh. Through high-throughput molecular docking with"],"journal":["Foods (Basel, Switzerland)"],"pubmed_title":["Identification of Bitter Peptides in &lt;i&gt;Lilium lancifolium&lt;/i&gt; Thunb.; Peptidomics, Computational Simulation and Cellular Functional Assays."],"pmcid":["PMC12692226"],"funding_grant_id":["2024RC2048","2021NK1005","2023JJ40339"],"pubmed_authors":["Sun M","Zhou L","He Y","Dong Z","Zeng J","Zhong X","Xiang W","Gong H","Huang P"],"additional_accession":[]},"is_claimable":false,"name":"Identification of Bitter Peptides in &lt;i&gt;Lilium lancifolium&lt;/i&gt; Thunb.; Peptidomics, Computational Simulation and Cellular Functional Assays.","description":"<i>Lilium lancifolium</i> Thunb., as a predominant variety of medicinal and edible lilies, has long been renowned in traditional medicine for \"moistening the lungs, relieving coughs, and calming the mind to soothe the heart.\" The bitter taste formation in <i>L. lancifolium</i> is predominantly attributed to secondary metabolites such as alkaloids, this study explores an alternative mechanism underlying taste divergence among <i>Lilium brownii</i> var. <i>viridulum</i>, and <i>Lilium pumilum</i> DC, proposing a foundational scientific question: Are peptides one of the important sources of bitterness in <i>Lilium lancifolium</i> Thunb.? Peptidomic analysis identified 8479 peptide sequences, with 46.27% upregulated in <i>L. lancifolium</i> flesh. Through high-throughput molecular docking with","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Nov","modification":"2026-05-26T17:05:49.95Z","creation":"2026-05-24T03:11:15.382Z"},"accession":"S-EPMC12692226","cross_references":{"pubmed":["41375993"],"doi":["10.3390/foods14234056"]}}