{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Li J"],"funding":["Xing Lu","Cuiyue Liang","Tianqi Wang"],"pagination":["3582"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12694265"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["14(23)"],"pubmed_abstract":["Heavy-metal-associated (HMA) isoprenylated plant proteins (HIPPs) play crucial roles in plant responses to biotic/abiotic stresses and heavy-metal homeostasis. However, the involvement of <i>HIPP</i> genes in the response of soybean (<i>Glycine max</i>) to aluminum (Al) toxicity remains unexplored. This study aimed to comprehensively characterize the <i>GmHIPP</i> gene family and investigate its role in Al toxicity. A total of 76 <i>GmHIPP</i> genes were identified in the soybean genome. Phylogenetic and synteny analyses revealed that HIPP evolution was highly conserved among soybean, Arabidopsis (<i>Arabidopsis thaliana</i>), and rice (<i>Oryza sativa</i>). Cis-element analysis indicated that <i>GmHIPP</i> genes might be involved in phytohormone response, abiotic and biotic stresses, and "],"journal":["Plants (Basel, Switzerland)"],"pubmed_title":["Characterization of the Soybean (&lt;i&gt;Glycine max&lt;/i&gt;) Heavy-Metal-Associated Isoprenylated Plant Protein (&lt;i&gt;HIPP&lt;/i&gt;) Gene Family in Response to Aluminum."],"pmcid":["PMC12694265"],"funding_grant_id":["2023YFD1901300","2022B0202060005","2024A1515013054","32302662","SGDX20210823103535007","2023ZD04072"],"pubmed_authors":["Tian J","Liang C","Li J","Lu X","Wang T"],"additional_accession":[]},"is_claimable":false,"name":"Characterization of the Soybean (&lt;i&gt;Glycine max&lt;/i&gt;) Heavy-Metal-Associated Isoprenylated Plant Protein (&lt;i&gt;HIPP&lt;/i&gt;) Gene Family in Response to Aluminum.","description":"Heavy-metal-associated (HMA) isoprenylated plant proteins (HIPPs) play crucial roles in plant responses to biotic/abiotic stresses and heavy-metal homeostasis. However, the involvement of <i>HIPP</i> genes in the response of soybean (<i>Glycine max</i>) to aluminum (Al) toxicity remains unexplored. This study aimed to comprehensively characterize the <i>GmHIPP</i> gene family and investigate its role in Al toxicity. A total of 76 <i>GmHIPP</i> genes were identified in the soybean genome. Phylogenetic and synteny analyses revealed that HIPP evolution was highly conserved among soybean, Arabidopsis (<i>Arabidopsis thaliana</i>), and rice (<i>Oryza sativa</i>). Cis-element analysis indicated that <i>GmHIPP</i> genes might be involved in phytohormone response, abiotic and biotic stresses, and ","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Nov","modification":"2026-05-26T11:02:08.308Z","creation":"2026-05-24T03:12:05.587Z"},"accession":"S-EPMC12694265","cross_references":{"pubmed":["41375292"],"doi":["10.3390/plants14233582"]}}