{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Nadel O"],"funding":["European Research Council"],"pagination":["434-442"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12695635"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["648(8093)"],"pubmed_abstract":["Marine picocyanobacteria are abundant photosynthetic organisms of global importance. They coexist in the ocean with cyanophages-viruses that infect cyanobacteria. Cyanophages carry many auxiliary metabolic genes acquired from their hosts that are thought to redirect host metabolism for the phage's benefit<sup>1-5</sup>. One such gene is nblA, which is present in multiple cyanophage families<sup>2,6-8</sup>. Under nutrient deprivation cyanobacterial NblA is responsible for inducing proteolytic degradation of the phycobilisome<sup>9-11</sup>, the large cyanobacterial photosynthetic light-harvesting complex. This increases the pool of amino acids available for essential tasks<sup>11</sup>, serving as a survival mechanism<sup>12</sup>. Ectopic expression of different cyanophage nblA genes resu"],"journal":["Nature"],"pubmed_title":["Viral NblA proteins negatively affect oceanic cyanobacterial photosynthesis."],"pmcid":["PMC12695635"],"funding_grant_id":["321647","646868"],"pubmed_authors":["Hanna R","Tahan R","Shitrit D","Kleifeld O","Rozenberg A","Lindell D","Beja O","Nadel O","Pekarsky I"],"additional_accession":[]},"is_claimable":false,"name":"Viral NblA proteins negatively affect oceanic cyanobacterial photosynthesis.","description":"Marine picocyanobacteria are abundant photosynthetic organisms of global importance. They coexist in the ocean with cyanophages-viruses that infect cyanobacteria. Cyanophages carry many auxiliary metabolic genes acquired from their hosts that are thought to redirect host metabolism for the phage's benefit<sup>1-5</sup>. One such gene is nblA, which is present in multiple cyanophage families<sup>2,6-8</sup>. Under nutrient deprivation cyanobacterial NblA is responsible for inducing proteolytic degradation of the phycobilisome<sup>9-11</sup>, the large cyanobacterial photosynthetic light-harvesting complex. This increases the pool of amino acids available for essential tasks<sup>11</sup>, serving as a survival mechanism<sup>12</sup>. Ectopic expression of different cyanophage nblA genes resu","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Dec","modification":"2026-07-15T11:16:07.656Z","creation":"2026-07-04T03:11:43.649Z"},"accession":"S-EPMC12695635","cross_references":{"pubmed":["41224996"],"doi":["10.1038/s41586-025-09656-x"]}}