biostudies-literatureXu LNational Basic Research Program of ChinaShanghai Municipal Education Commission-Gaofeng Clinical Medicine2589586https://www.ebi.ac.uk/biostudies/studies/S-EPMC12697273biostudies-literatureUnknown47(1)This study investigated the clinical outcomes and mortality risks in elderly peritoneal dialysis (PD) patients with diabetes mellitus (DM). A total of 210 incident PD patients aged 70 years or older (mean age 80.7 ± 5.0 years; 60.5% men) who initiated treatment between 2009 and 2020 were analyzed, including 81 (38.6%) with DM. Compared with non-diabetic patients, those with DM were younger (79.6 ± 4.7 vs. 81.4 ± 5.0 years, <i>p</i> = 0.011), and had higher fasting glucose (6.18 [4.53-9.30] vs. 4.88 [4.40-5.63] mmol/L, <i>p</i> < 0.001) and HbA1c (6.10% [5.43-6.78] vs. 5.40% [5.00-5.70], <i>p</i> < 0.001). Annualized mortality was 0.22 deaths per patient-year (95% CI 0.16-0.29) in the DM group and 0.20 (95% CI 0.16-0.25) in the non-DM group. Kaplan-Meier survival analysis revealed no signifRenal failureImpact of diabetes on survival and clinical outcomes in elderly patients receiving peritoneal dialysis.PMC12697273201522118137086481670691Xu LNi ZQian YLi ZHuang JFang WSong QGu LYu ZYan HJiang NYuan JfalseImpact of diabetes on survival and clinical outcomes in elderly patients receiving peritoneal dialysis.This study investigated the clinical outcomes and mortality risks in elderly peritoneal dialysis (PD) patients with diabetes mellitus (DM). A total of 210 incident PD patients aged 70 years or older (mean age 80.7 ± 5.0 years; 60.5% men) who initiated treatment between 2009 and 2020 were analyzed, including 81 (38.6%) with DM. Compared with non-diabetic patients, those with DM were younger (79.6 ± 4.7 vs. 81.4 ± 5.0 years, <i>p</i> = 0.011), and had higher fasting glucose (6.18 [4.53-9.30] vs. 4.88 [4.40-5.63] mmol/L, <i>p</i> < 0.001) and HbA1c (6.10% [5.43-6.78] vs. 5.40% [5.00-5.70], <i>p</i> < 0.001). Annualized mortality was 0.22 deaths per patient-year (95% CI 0.16-0.29) in the DM group and 0.20 (95% CI 0.16-0.25) in the non-DM group. Kaplan-Meier survival analysis revealed no signif2025-01-01T00:00:00Z2025 Dec2026-05-26T17:04:12.16Z2026-05-24T03:11:42.264ZS-EPMC126972734137161710.1080/0886022X.2025.2589586