biostudies-literatureUnknown5(5)Samaha JN<h4>Background</h4>Achieving excellent recanalization (Modified Thrombolysis in Cerebral Infarction 2c/3) in fewer attempts improves clinical outcomes. Previous studies suggest that switching techniques after a failed first pass may enhance reperfusion rates. This study evaluates whether technique switching improves subsequent reperfusion in a large multicenter registry.<h4>Methods</h4>We analyzed retrospective and prospective SVIN (Society of Vascular and Interventional Neurology) registry data from 12 US centers (October 2014-December 2021) involving endovascular therapy for M1 or internal carotid artery-terminus (ICA-T) occlusions. Patients with at least 2 recanalization attempts using stent retriever (SR), contact aspiration (CA), or combined technique (CT) were included. Primary outcoStroke (Hoboken, N.J.)e001797https://www.ebi.ac.uk/biostudies/studies/S-EPMC12697647biostudies-literatureEndovascular Thrombectomy Technique Optimization: A SVIN Registry Analysis.PMC12697647Iyyangar ASAbdelhakim NMiller SEZhang LAbdalkader MHaussen DCAl-Bayati ARLiebeskind DSDolia JHassan AENguyen TNSugg RMNogueira RGAzeem HSheth SAJumaa MABajaj RLinares GDabus GMajidi SMehta BPFifi JTKhalife JMohammaden MReddi PKoneru MGrossberg JASessa JTekle WGOrtega-Gutierrez SGalecio-Castillo MCespedes JSaei HMLinfante ILe NMSamaha JNfalseEndovascular Thrombectomy Technique Optimization: A SVIN Registry Analysis.<h4>Background</h4>Achieving excellent recanalization (Modified Thrombolysis in Cerebral Infarction 2c/3) in fewer attempts improves clinical outcomes. Previous studies suggest that switching techniques after a failed first pass may enhance reperfusion rates. This study evaluates whether technique switching improves subsequent reperfusion in a large multicenter registry.<h4>Methods</h4>We analyzed retrospective and prospective SVIN (Society of Vascular and Interventional Neurology) registry data from 12 US centers (October 2014-December 2021) involving endovascular therapy for M1 or internal carotid artery-terminus (ICA-T) occlusions. Patients with at least 2 recanalization attempts using stent retriever (SR), contact aspiration (CA), or combined technique (CT) were included. Primary outco2025-01-01T00:00:00Z2025 Sep2026-06-06T21:51:21.649Z2026-06-05T03:11:48.09ZS-EPMC126976474157333110.1161/SVIN.125.001797