{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["28"],"submitter":["Maatouk M"],"pubmed_abstract":["<h4>Background</h4>Recently, renewed concern has been centered on the role of the mesentery in the development of Crohn's disease (CD). However, there are minimal data supporting the extended mesenteric excision (EME), which may lead to reticence in the adoption of this surgical option. This systematic review and meta-analysis aimed to compare the post-operative outcomes in patients undergoing EME vs limited mesenteric excision (LME) for CD.<h4>Methods</h4>We conducted a systematic search from January 2018 to January 2025 for studies reporting outcomes in patients undergoing EME compared with LME for CD. A pooled meta-analysis was performed. The risk of bias was examined using the ROBINS-I v2 and RoB2 tool.<h4>Results</h4>Nine studies were included in final analysis, comprising two randomi"],"journal":["Surgery open science"],"pagination":["89-97"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12704082"],"repository":["biostudies-literature"],"pubmed_title":["Mesenteric inclusion in Crohn's disease surgery: Promising breakthrough or tempest in a teapot? An updated meta-analysis."],"pmcid":["PMC12704082"],"pubmed_authors":["Khalifa MB","Nouira M","Maatouk M","Boudokhane M","Mabrouk A","Moussa MB","Essid N"],"additional_accession":[]},"is_claimable":false,"name":"Mesenteric inclusion in Crohn's disease surgery: Promising breakthrough or tempest in a teapot? An updated meta-analysis.","description":"<h4>Background</h4>Recently, renewed concern has been centered on the role of the mesentery in the development of Crohn's disease (CD). However, there are minimal data supporting the extended mesenteric excision (EME), which may lead to reticence in the adoption of this surgical option. This systematic review and meta-analysis aimed to compare the post-operative outcomes in patients undergoing EME vs limited mesenteric excision (LME) for CD.<h4>Methods</h4>We conducted a systematic search from January 2018 to January 2025 for studies reporting outcomes in patients undergoing EME compared with LME for CD. A pooled meta-analysis was performed. The risk of bias was examined using the ROBINS-I v2 and RoB2 tool.<h4>Results</h4>Nine studies were included in final analysis, comprising two randomi","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Dec","modification":"2026-06-06T04:19:14.414Z","creation":"2026-05-25T03:12:00.581Z"},"accession":"S-EPMC12704082","cross_references":{"pubmed":["41403856"],"doi":["10.1016/j.sopen.2025.10.010"]}}