{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["57(1)"],"submitter":["Cai Z"],"pubmed_abstract":["<h4>Background</h4>Extrapancreatic perineural invasion (EPNI) was an adverse prognostic factor in patients with pancreatic ductal adenocarcinoma (PDAC) and responsible for positive resection margin. This study aimed to develop an automatic model for segmenting the extrapancreatic nerve plexus and diagnosing EPNI.<h4>Methods</h4>In this retrospective study, patients diagnosed with PDAC who underwent enhanced computer tomography scans between August 2018 and December 2022 were enrolled. These cases were divided into training sets with radiological EPNI labels, and validation sets with pathological EPNI labels. The extrapancreatic nerve plexus was segmented first <i>via</i> the nnUNet network and attention mechanism under the background of segmentation of PDAC and adjacent vessels. A 2D class"],"journal":["Annals of medicine"],"pagination":["2568116"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12704129"],"repository":["biostudies-literature"],"pubmed_title":["Deep learning to predict extrapancreatic perineural invasion at CT images."],"pmcid":["PMC12704129"],"pubmed_authors":["Qiu Y","Zou L","Chen J","Cai Z","Li Q","Ji J","Mao L"],"additional_accession":[]},"is_claimable":false,"name":"Deep learning to predict extrapancreatic perineural invasion at CT images.","description":"<h4>Background</h4>Extrapancreatic perineural invasion (EPNI) was an adverse prognostic factor in patients with pancreatic ductal adenocarcinoma (PDAC) and responsible for positive resection margin. This study aimed to develop an automatic model for segmenting the extrapancreatic nerve plexus and diagnosing EPNI.<h4>Methods</h4>In this retrospective study, patients diagnosed with PDAC who underwent enhanced computer tomography scans between August 2018 and December 2022 were enrolled. These cases were divided into training sets with radiological EPNI labels, and validation sets with pathological EPNI labels. The extrapancreatic nerve plexus was segmented first <i>via</i> the nnUNet network and attention mechanism under the background of segmentation of PDAC and adjacent vessels. A 2D class","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Dec","modification":"2026-06-06T03:50:02.372Z","creation":"2026-05-25T03:12:03.542Z"},"accession":"S-EPMC12704129","cross_references":{"pubmed":["41388696"],"doi":["10.1080/07853890.2025.2568116"]}}