{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["15(58)"],"submitter":["Tran LVH"],"pubmed_abstract":["<i>Nelumbo nucifera</i> Gaertn. has been used as a traditional medicine and food. To date, many unknown constituents have been discovered. Most of the researches on secondary metabolites and their pharmacological properties focus on alkaloid derivatives. In this study, a novel pyrrole terpenoid hydrid, lotusin A (1), and five reported substances, cholestanol (2), stigmast-4-en-3-one (3), quercetin (4), isorhamnetin (5), and norartocarpetin (6), were isolated from the methanol extract of the roots of <i>N. nucifera</i> Gaertn. The structures (1-6) were identified <i>via</i> spectroscopic analyses of NMR (1D and 2D), HR-ESIMS, and comparisons with those previously reported in the literature. Compound 1, a pyrrole terpenoid hydrid, is a unique isolate from plant natural products. Compounds 1 "],"journal":["RSC advances"],"pagination":["50103-50110"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12705226"],"repository":["biostudies-literature"],"pubmed_title":["Lotusin A: a novel pyrrole terpenoid hydrid from lotus roots (&lt;i&gt;Nelumbo nucifera&lt;/i&gt; Gaertn.)."],"pmcid":["PMC12705226"],"pubmed_authors":["Hoang Long T","Tran LVH","La VH","Phan TT","Ton That Q","Le DT","Vo HC","Thai KM","Thi Thuy Duong N","Le MT","Le QT","Nguyen MC","Tran L","Tran HNK","Nguyen TDL","Hoang LT"],"additional_accession":[]},"is_claimable":false,"name":"Lotusin A: a novel pyrrole terpenoid hydrid from lotus roots (&lt;i&gt;Nelumbo nucifera&lt;/i&gt; Gaertn.).","description":"<i>Nelumbo nucifera</i> Gaertn. has been used as a traditional medicine and food. To date, many unknown constituents have been discovered. Most of the researches on secondary metabolites and their pharmacological properties focus on alkaloid derivatives. In this study, a novel pyrrole terpenoid hydrid, lotusin A (1), and five reported substances, cholestanol (2), stigmast-4-en-3-one (3), quercetin (4), isorhamnetin (5), and norartocarpetin (6), were isolated from the methanol extract of the roots of <i>N. nucifera</i> Gaertn. The structures (1-6) were identified <i>via</i> spectroscopic analyses of NMR (1D and 2D), HR-ESIMS, and comparisons with those previously reported in the literature. Compound 1, a pyrrole terpenoid hydrid, is a unique isolate from plant natural products. Compounds 1 ","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Dec","modification":"2026-06-13T04:47:49.491Z","creation":"2026-06-13T03:08:56.51Z"},"accession":"S-EPMC12705226","cross_references":{"pubmed":["41403672"],"doi":["10.1039/d5ra05354d"]}}