biostudies-literatureUnknown83(1)Kissock K<h4>Background</h4>Large between-person differences in blood pressure (BP) responses to sodium reduction, potassium supplementation, and potassium-enriched salt have been suggested by prior studies. However, limitations in research designs and misinterpretation of findings mean that overestimation of true between-person variation in response is likely.<h4>Methods</h4>Systolic BP (SBP) response during a 4-week run-in period on potassium-enriched salt was measured for 608 individuals. Participants were defined as apparently sensitive if SBP fell and apparently resistant if SBP was unchanged or rose. The effect of potassium-enriched salt compared with regular salt on SBP was then compared for apparently sensitive versus apparently resistant groups over a subsequent 12-month postrandomization Hypertension (Dallas, Tex. : 1979)167-176https://www.ebi.ac.uk/biostudies/studies/S-EPMC12711297biostudies-literatureConsistency of Blood Pressure Response to Potassium-Enriched Salt in the China Salt Substitute Study.PMC12711297Wang NNeal BRodgers AKissock KHuang LSundstrom JJonsson HWu YYuan YfalseConsistency of Blood Pressure Response to Potassium-Enriched Salt in the China Salt Substitute Study.<h4>Background</h4>Large between-person differences in blood pressure (BP) responses to sodium reduction, potassium supplementation, and potassium-enriched salt have been suggested by prior studies. However, limitations in research designs and misinterpretation of findings mean that overestimation of true between-person variation in response is likely.<h4>Methods</h4>Systolic BP (SBP) response during a 4-week run-in period on potassium-enriched salt was measured for 608 individuals. Participants were defined as apparently sensitive if SBP fell and apparently resistant if SBP was unchanged or rose. The effect of potassium-enriched salt compared with regular salt on SBP was then compared for apparently sensitive versus apparently resistant groups over a subsequent 12-month postrandomization 2026-01-01T00:00:00Z2026 Jan2026-07-15T11:14:27.204Z2026-07-04T03:12:25.522ZS-EPMC127112974126307110.1161/HYPERTENSIONAHA.125.24723