{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["13(12)"],"submitter":["Haddock NT"],"pubmed_abstract":["<h4>Background</h4>Breast reconstruction after mastectomy improves quality of life for breast cancer patients. As more late-stage patients undergo reconstruction, it is essential to understand how treatment regimens and radiation impact outcomes. This study compared early- and late-stage breast cancer patients, examining comorbidities, reconstructive details, complications, and satisfaction.<h4>Methods</h4>A total of 989 patients (903 early-stage; 86 late-stage) who underwent breast reconstruction between January 2011 and February 2025 were reviewed. Cancer staging followed the National Cancer Institute definitions: early-stage (I-IIIA) and late-stage (IIIB-IV).<h4>Results</h4>Late-stage patients had higher rates of diabetes (<i>P</i> = 0.003), neoadjuvant chemotherapy (<i>P</i> < 0.001), "],"journal":["Plastic and reconstructive surgery. Global open"],"pagination":["e7361"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12711366"],"repository":["biostudies-literature"],"pubmed_title":["Exploring Breast Reconstruction in Late-stage Breast Cancer Patients."],"pmcid":["PMC12711366"],"pubmed_authors":["Haddock NT","Troia TC","Teotia SS","Kim LJ"],"additional_accession":[]},"is_claimable":false,"name":"Exploring Breast Reconstruction in Late-stage Breast Cancer Patients.","description":"<h4>Background</h4>Breast reconstruction after mastectomy improves quality of life for breast cancer patients. As more late-stage patients undergo reconstruction, it is essential to understand how treatment regimens and radiation impact outcomes. This study compared early- and late-stage breast cancer patients, examining comorbidities, reconstructive details, complications, and satisfaction.<h4>Methods</h4>A total of 989 patients (903 early-stage; 86 late-stage) who underwent breast reconstruction between January 2011 and February 2025 were reviewed. Cancer staging followed the National Cancer Institute definitions: early-stage (I-IIIA) and late-stage (IIIB-IV).<h4>Results</h4>Late-stage patients had higher rates of diabetes (<i>P</i> = 0.003), neoadjuvant chemotherapy (<i>P</i> < 0.001), ","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Dec","modification":"2026-06-07T05:26:20.374Z","creation":"2026-06-07T03:07:13.257Z"},"accession":"S-EPMC12711366","cross_references":{"pubmed":["41415597"],"doi":["10.1097/GOX.0000000000007361"]}}