{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Haljasmagi L"],"funding":["Eesti Teadusagentuur","European Union through HORIZON Coordination and Support Actions"],"pagination":["e70100"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12712876"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["55(12)"],"pubmed_abstract":["Selecting a sensitive test system is crucial to measure IFNα in serum samples. Simoa digital ELISA stands out for its high sensitivity and strong correlation with transcript-based IFN-induced gene (ISG) scores. In SLE, the ISG score is explained by circulating IFNα levels with negligible contribution from IFNβ or IFNγ. Created in BioRender."],"journal":["European journal of immunology"],"pubmed_title":["Ultrasensitive Test Systems Are Required to Quantify Interferon Alpha Protein in Serum Samples."],"pmcid":["PMC12712876"],"funding_grant_id":["101159920","PRG1117"],"pubmed_authors":["Duffy D","Kisand K","Peterson P","Meisalu S","Haljasmagi L","Bondet V"],"additional_accession":[]},"is_claimable":false,"name":"Ultrasensitive Test Systems Are Required to Quantify Interferon Alpha Protein in Serum Samples.","description":"Selecting a sensitive test system is crucial to measure IFNα in serum samples. Simoa digital ELISA stands out for its high sensitivity and strong correlation with transcript-based IFN-induced gene (ISG) scores. In SLE, the ISG score is explained by circulating IFNα levels with negligible contribution from IFNβ or IFNγ. Created in BioRender.","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Dec","modification":"2026-06-06T05:07:58.534Z","creation":"2026-05-26T03:12:11.68Z"},"accession":"S-EPMC12712876","cross_references":{"pubmed":["41410169"],"doi":["10.1002/eji.70100"]}}