{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["134(8)"],"submitter":["Singha KP"],"pubmed_abstract":["The effects of high plant-based proteins (PP) used as alternative protein sources in aquafeeds on muscle cellularity and myogenic factors of rainbow trout, <i>Oncorhynchus mykiss</i>, remain unclear. This study explored muscle fibre growth phases and the impact of two additive mixtures (A) in high-PP diets on muscle physiology. Over a seven-month trial, 2000 fish (2·22 g) were divided into four groups (five replicates each) and fed isonitrogenous (fry, 46 %; fingerling, 44 %; and grow-out, 42 % crude protein) and isolipidic (20 % lipid) diets: control (30 % fishmeal), PP, PP + A1 (krill meal, taurine, selenium) and PP + A2 (proline, hydroxyproline, vitamin C). Sampling for muscle histology and myogenic gene expression was conducted at ten sampling points from Day 0 to Day 214. Muscle histo"],"journal":["The British journal of nutrition"],"pagination":["617-633"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12722011"],"repository":["biostudies-literature"],"pubmed_title":["Muscle hyperplasia and hypertrophy dynamics in rainbow trout (&lt;i&gt;Oncorhynchus mykiss&lt;/i&gt;): impact of high plant-based protein and additive mixtures on muscle physiology."],"pmcid":["PMC12722011"],"pubmed_authors":["Kumar V","Phelps M","Overturf K","Singha KP"],"additional_accession":[]},"is_claimable":false,"name":"Muscle hyperplasia and hypertrophy dynamics in rainbow trout (&lt;i&gt;Oncorhynchus mykiss&lt;/i&gt;): impact of high plant-based protein and additive mixtures on muscle physiology.","description":"The effects of high plant-based proteins (PP) used as alternative protein sources in aquafeeds on muscle cellularity and myogenic factors of rainbow trout, <i>Oncorhynchus mykiss</i>, remain unclear. This study explored muscle fibre growth phases and the impact of two additive mixtures (A) in high-PP diets on muscle physiology. Over a seven-month trial, 2000 fish (2·22 g) were divided into four groups (five replicates each) and fed isonitrogenous (fry, 46 %; fingerling, 44 %; and grow-out, 42 % crude protein) and isolipidic (20 % lipid) diets: control (30 % fishmeal), PP, PP + A1 (krill meal, taurine, selenium) and PP + A2 (proline, hydroxyproline, vitamin C). Sampling for muscle histology and myogenic gene expression was conducted at ten sampling points from Day 0 to Day 214. Muscle histo","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Oct","modification":"2026-06-06T05:26:12.926Z","creation":"2026-05-26T03:12:25.191Z"},"accession":"S-EPMC12722011","cross_references":{"pubmed":["40983595"],"doi":["10.1017/S0007114525105175"]}}