biostudies-literatureGu WThe Multicenter Clinical Research Project of Shanghai Jiao Tong University School of MedicineNational Natural Science Foundation of ChinaShanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Nucleic Acid Chemistry and Nanomedicine, "Clinical+" Excellence ProjectInstitute of Molecular Medicine, the Shanghai Medical Youth Talent Training and Support Program700https://www.ebi.ac.uk/biostudies/studies/S-EPMC12723906biostudies-literatureUnknown26(1)<h4>Background</h4>Home-based dialysis, including peritoneal dialysis (PD) and home hemodialysis (HHD), has been suggested to reduce SARS-CoV-2 infection rates and improve outcomes compared to in-center dialysis, yet evidence from China remains scarce.<h4>Objective</h4>To investigate the risk and prognosis of Omicron infection among patients receiving home-based dialysis versus in-center dialysis during the Omicron surge in Shanghai, China.<h4>Methods</h4>This single-center retrospective cohort study included patients undergoing maintenance dialysis (home-based dialysis or in-center dialysis) at Ren Ji Hospital from December 1, 2022, to January 31, 2023. The primary endpoint was Omicron infection rate; secondary endpoints included infection timeline, all-cause mortality, and associated risBMC nephrologyRisk and prognosis of Omicron infection in home-based dialysis patients: a retrospective cohort study in China.PMC127239062024ZY004DLY2018058240079082070693[2025]71Huang JGu WZhang HZhou YGu AFang YNi ZShao XJin HLi ZWang QFang WGu LGu JYan HLu RfalseRisk and prognosis of Omicron infection in home-based dialysis patients: a retrospective cohort study in China.<h4>Background</h4>Home-based dialysis, including peritoneal dialysis (PD) and home hemodialysis (HHD), has been suggested to reduce SARS-CoV-2 infection rates and improve outcomes compared to in-center dialysis, yet evidence from China remains scarce.<h4>Objective</h4>To investigate the risk and prognosis of Omicron infection among patients receiving home-based dialysis versus in-center dialysis during the Omicron surge in Shanghai, China.<h4>Methods</h4>This single-center retrospective cohort study included patients undergoing maintenance dialysis (home-based dialysis or in-center dialysis) at Ren Ji Hospital from December 1, 2022, to January 31, 2023. The primary endpoint was Omicron infection rate; secondary endpoints included infection timeline, all-cause mortality, and associated ris2025-01-01T00:00:00Z2025 Dec2026-06-06T04:54:36.02Z2026-05-25T03:12:15.857ZS-EPMC127239064143693910.1186/s12882-025-04453-0