{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["61(12)"],"submitter":["Brugiatelli L"],"pubmed_abstract":["Infective endocarditis (IE) is a life-threatening condition with a rising incidence, demanding rapid and precise diagnosis. While echocardiography remains the cornerstone of initial evaluation, its limitations in complex cases-such as those involving prosthetic valves or cardiac devices-are well-known. This review synthesizes current evidence and guidelines to outline a practical, multimodality imaging approach for IE. We emphasize that integrating advanced techniques like cardiac computed tomography (CT) and [18F]-fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) early in the diagnostic pathway, particularly in high-risk scenarios, significantly enhances diagnostic certainty, guides therapeutic decisions, and improves patient outcomes. A tailored imaging str"],"journal":["Medicina (Kaunas, Lithuania)"],"pagination":["2241"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12735077"],"repository":["biostudies-literature"],"pubmed_title":["Multimodality Imaging in Infective Endocarditis: A Clinical Approach to Diagnosis."],"pmcid":["PMC12735077"],"pubmed_authors":["Enrico P","Capodaglio I","Brugiatelli L","Marco N","Simone L","Patani F","Benedetta A","Giulia P","Marco F","Marco M","Lofiego C","Marco DE","Vagnarelli F","Benedetti M","Nicolo S","Arianna M","Maurizi K","Antonio DR","Giulia F","Chiara G","Giovanni T","Matteo F"],"additional_accession":[]},"is_claimable":false,"name":"Multimodality Imaging in Infective Endocarditis: A Clinical Approach to Diagnosis.","description":"Infective endocarditis (IE) is a life-threatening condition with a rising incidence, demanding rapid and precise diagnosis. While echocardiography remains the cornerstone of initial evaluation, its limitations in complex cases-such as those involving prosthetic valves or cardiac devices-are well-known. This review synthesizes current evidence and guidelines to outline a practical, multimodality imaging approach for IE. We emphasize that integrating advanced techniques like cardiac computed tomography (CT) and [18F]-fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) early in the diagnostic pathway, particularly in high-risk scenarios, significantly enhances diagnostic certainty, guides therapeutic decisions, and improves patient outcomes. A tailored imaging str","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Dec","modification":"2026-05-27T08:01:45.984Z","creation":"2026-05-27T03:12:33.158Z"},"accession":"S-EPMC12735077","cross_references":{"pubmed":["41470242"],"doi":["10.3390/medicina61122241"]}}