{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["30(24)"],"submitter":["Bakirova RY"],"pubmed_abstract":["An important aspect of food technology is that vitamin compounds can be used for a variety of purposes, such as developing methods to enhance the nutritional value of foods. This paper discusses the synthesis and properties of β-cyclodextrin (β-CD)-functionalized silver nanoparticles, and the use of the resulting β-CD-AgNP inclusion complex when loading vitamin D<sub>3</sub> (cholecalciferol, VD<sub>3</sub>) molecules. β-Cyclodextrin was used as a reducing agent and a stabilizer in the production of silver nanoparticles. The preparation of VD<sub>3</sub>-β-CD-AgNP nanocompositions was confirmed by UV spectroscopy, transmission electron microscopy, and X-ray diffraction spectroscopy. Scanning electron microscopy (SEM) and transmission electron microscopy (TEM) revealed that the resulting β-CD-VD<sub>3</sub>-AgNP nanocomposite was well dispersed with particle sizes ranging from 6 to 15 nm. <sup>1</sup>H-, <sup>13</sup>C-NMR and FTIR spectroscopy showed the reduction of silver ions and the formation of β-CD-encapsulated AgNPs. The kinetic parameters of the thermal decomposition reaction of the VD<sub>3</sub>-β-CD-AgNP nanocomposition have been determined under nonisothermal conditions that ensure the preservation of the kinetic triplet and a more accurate description of the process. The nanocomposition of VD<sub>3</sub> with silver nanoparticles demonstrated antibacterial activity against the used bacteria."],"journal":["Molecules (Basel, Switzerland)"],"pagination":["4823"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12735546"],"repository":["biostudies-literature"],"pubmed_title":["Preparation of a Supramolecular Assembly of Vitamin D in a β-Cyclodextrin Shell with Silver Nanoparticles."],"pmcid":["PMC12735546"],"pubmed_authors":["Agedilova MT","Ashirbekova BD","Mendibayeva AZ","Sviderskiy AK","Mustafayeva AK","Khabdolda G","Bakirova RY","Iskineyeva AS","Fazylov SD","Sarsenbekova AZ","Seilkhanov OT"],"additional_accession":[]},"is_claimable":false,"name":"Preparation of a Supramolecular Assembly of Vitamin D in a β-Cyclodextrin Shell with Silver Nanoparticles.","description":"An important aspect of food technology is that vitamin compounds can be used for a variety of purposes, such as developing methods to enhance the nutritional value of foods. This paper discusses the synthesis and properties of β-cyclodextrin (β-CD)-functionalized silver nanoparticles, and the use of the resulting β-CD-AgNP inclusion complex when loading vitamin D<sub>3</sub> (cholecalciferol, VD<sub>3</sub>) molecules. β-Cyclodextrin was used as a reducing agent and a stabilizer in the production of silver nanoparticles. The preparation of VD<sub>3</sub>-β-CD-AgNP nanocompositions was confirmed by UV spectroscopy, transmission electron microscopy, and X-ray diffraction spectroscopy. Scanning electron microscopy (SEM) and transmission electron microscopy (TEM) revealed that the resulting β-CD-VD<sub>3</sub>-AgNP nanocomposite was well dispersed with particle sizes ranging from 6 to 15 nm. <sup>1</sup>H-, <sup>13</sup>C-NMR and FTIR spectroscopy showed the reduction of silver ions and the formation of β-CD-encapsulated AgNPs. The kinetic parameters of the thermal decomposition reaction of the VD<sub>3</sub>-β-CD-AgNP nanocomposition have been determined under nonisothermal conditions that ensure the preservation of the kinetic triplet and a more accurate description of the process. The nanocomposition of VD<sub>3</sub> with silver nanoparticles demonstrated antibacterial activity against the used bacteria.","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Dec","modification":"2026-06-10T03:08:15.514Z","creation":"2026-06-10T03:07:03.394Z"},"accession":"S-EPMC12735546","cross_references":{"pubmed":["41471844"],"doi":["10.3390/molecules30244823"]}}