{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Ruan J"],"funding":["the Xinjiang Uygur Autonomous Region Science and Technology Program Project","Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine"],"pagination":["4754"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12736087"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["30(24)"],"pubmed_abstract":["This study focuses on polysaccharides from <i>Cistanche deserticola</i> and <i>Cistanche tubulosa</i>, medicinal plants renowned for their health benefits. The \"water extraction and alcohol precipitation\" method was used to obtain the crude polysaccharides of the wine-making residues of <i>C. deserticola</i> (CDP) and <i>C. tubulosa</i> (CTP), respectively. Then, ultrafiltration membrane (UFM), DEAE-52, and Sephadex-G75 or Smartdex-G100 gel chromatography were used to separate and purify the crude polysaccharides, yielding the homogeneous fractions <b>CDP1-5-1</b>, <b>CDP2-2-2</b>, <b>CDP2-3-2</b>, <b>CTP1-5-1</b>, and <b>CTP1-5-3</b>. Structural analysis was conducted by using Fourier-transform infrared spectroscopy (FT-IR), high-performance anion-exchange chromatography coupled with mult"],"journal":["Molecules (Basel, Switzerland)"],"pubmed_title":["Comparison of Extraction, Isolation, Purification, Structural Characterization and Immunomodulatory Activity of Polysaccharides from Two Species of &lt;i&gt;Cistanche&lt;/i&gt;."],"pmcid":["PMC12736087"],"funding_grant_id":["2022LQ04007","ZYYCXTD-C-202009"],"pubmed_authors":["Ruan J","Yu L","Chen A","Zhang J","Zhang Y","Wang D","Wang T","Zhang P"],"additional_accession":[]},"is_claimable":false,"name":"Comparison of Extraction, Isolation, Purification, Structural Characterization and Immunomodulatory Activity of Polysaccharides from Two Species of &lt;i&gt;Cistanche&lt;/i&gt;.","description":"This study focuses on polysaccharides from <i>Cistanche deserticola</i> and <i>Cistanche tubulosa</i>, medicinal plants renowned for their health benefits. The \"water extraction and alcohol precipitation\" method was used to obtain the crude polysaccharides of the wine-making residues of <i>C. deserticola</i> (CDP) and <i>C. tubulosa</i> (CTP), respectively. Then, ultrafiltration membrane (UFM), DEAE-52, and Sephadex-G75 or Smartdex-G100 gel chromatography were used to separate and purify the crude polysaccharides, yielding the homogeneous fractions <b>CDP1-5-1</b>, <b>CDP2-2-2</b>, <b>CDP2-3-2</b>, <b>CTP1-5-1</b>, and <b>CTP1-5-3</b>. Structural analysis was conducted by using Fourier-transform infrared spectroscopy (FT-IR), high-performance anion-exchange chromatography coupled with mult","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Dec","modification":"2026-05-27T08:03:09.683Z","creation":"2026-05-27T03:12:10.908Z"},"accession":"S-EPMC12736087","cross_references":{"pubmed":["41471780"],"doi":["10.3390/molecules30244754"]}}