{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Shen D"],"funding":["STI 2030-Major Projects"],"pagination":["1167"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12752173"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["25(1)"],"pubmed_abstract":["<h4>Background</h4>Methamphetamine (METH)-induced psychosis (MAP), characterized by transient schizophreniform symptoms, affects approximately 43% of individuals with methamphetamine use disorders (MUD). However, the cortical atrophy pattern associated with MAP remain unclear.<h4>Methods</h4>Ninety-four male patients with MUD (62 without psychotic symptoms [MA] and 32 MAP) and 61 healthy controls (HCs) underwent high-resolution T1-weighted MRI and clinical assessments. Surface-based morphological (SBM) analysis using FreeSurfer 7.1.1 was conducted to explore cortical thickness and volume difference among groups. We also examined the correlation between brain structural changes and clinical variables.<h4>Results</h4>The MAP group showed significant cortical thinning in the left superior tem"],"journal":["BMC psychiatry"],"pubmed_title":["Cortical morphological alterations in methamphetamine-induced psychosis: a surface-based morphometry study."],"pmcid":["PMC12752173"],"funding_grant_id":["2021ZD0202105"],"pubmed_authors":["Li J","Tao H","Shen D","Lai M","Xu J","Luo D"],"additional_accession":[]},"is_claimable":false,"name":"Cortical morphological alterations in methamphetamine-induced psychosis: a surface-based morphometry study.","description":"<h4>Background</h4>Methamphetamine (METH)-induced psychosis (MAP), characterized by transient schizophreniform symptoms, affects approximately 43% of individuals with methamphetamine use disorders (MUD). However, the cortical atrophy pattern associated with MAP remain unclear.<h4>Methods</h4>Ninety-four male patients with MUD (62 without psychotic symptoms [MA] and 32 MAP) and 61 healthy controls (HCs) underwent high-resolution T1-weighted MRI and clinical assessments. Surface-based morphological (SBM) analysis using FreeSurfer 7.1.1 was conducted to explore cortical thickness and volume difference among groups. We also examined the correlation between brain structural changes and clinical variables.<h4>Results</h4>The MAP group showed significant cortical thinning in the left superior tem","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Nov","modification":"2026-06-06T08:35:16.317Z","creation":"2026-05-27T03:12:35.866Z"},"accession":"S-EPMC12752173","cross_references":{"pubmed":["41257616"],"doi":["10.1186/s12888-025-07603-8"]}}