{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["10(1)"],"submitter":["Asano D"],"pubmed_abstract":["<h4>Background</h4>Surgical resection for neuroendocrine liver metastasis (NELM) is the key to long survival; however, the indications remain unclear due to the high recurrence rate. We aimed to identify candidates who would benefit from surgical resection for NELM.<h4>Methods</h4>Patients with NELM treated at our institution from January 2005 to December 2020 were included. Neuroendocrine carcinoma (NEC) was excluded. Risk factors for overall survival (OS) and recurrence-free survival (RFS) were analyzed. The cut-off value for the number of NELM predicting poor RFS was determined by minimum <i>p</i>-value approach.<h4>Results</h4>Of the total 126 patients, 67 patients underwent liver resection. The median follow-up time from the date of initial diagnosis of NELM was 4.3 years. Surgical re"],"journal":["Annals of Gastroenterological Surgery"],"pagination":["219-228"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12757151"],"repository":["biostudies-literature"],"pubmed_title":["Indications for Surgical Resection in Patients With Neuroendocrine Tumor Liver Metastases: An Intensive Surgical Experience of a High-Volume Center."],"pmcid":["PMC12757151"],"pubmed_authors":["Sugawara T","Gan S","Watanabe S","Asano D","Akahoshi K","Ishikawa Y","Motohashi S","Ban D","Kudo A","Ueda H"],"additional_accession":[]},"is_claimable":false,"name":"Indications for Surgical Resection in Patients With Neuroendocrine Tumor Liver Metastases: An Intensive Surgical Experience of a High-Volume Center.","description":"<h4>Background</h4>Surgical resection for neuroendocrine liver metastasis (NELM) is the key to long survival; however, the indications remain unclear due to the high recurrence rate. We aimed to identify candidates who would benefit from surgical resection for NELM.<h4>Methods</h4>Patients with NELM treated at our institution from January 2005 to December 2020 were included. Neuroendocrine carcinoma (NEC) was excluded. Risk factors for overall survival (OS) and recurrence-free survival (RFS) were analyzed. The cut-off value for the number of NELM predicting poor RFS was determined by minimum <i>p</i>-value approach.<h4>Results</h4>Of the total 126 patients, 67 patients underwent liver resection. The median follow-up time from the date of initial diagnosis of NELM was 4.3 years. Surgical re","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Jan","modification":"2026-05-29T03:17:53.032Z","creation":"2026-05-29T03:11:46.685Z"},"accession":"S-EPMC12757151","cross_references":{"pubmed":["41488831"],"doi":["10.1002/ags3.70082"]}}