biostudies-literatureLi YNational Science Fund for Distinguished Young ScholarsShaanxi Fundamental Science Research Project for Chemistry & Biologye20814https://www.ebi.ac.uk/biostudies/studies/S-EPMC12759195biostudies-literatureUnknown65(1)Controlling the assembly of molecular nanocapsules through metal-carbon bonds constitutes a major challenge in the field of supramolecular organometallic chemistry. Here, we demonstrate the construction of two nanosized dodecanuclear organometallic capsules, [{Ag(CH₃CN)₄(BF₄)₈}⊂Ag₁₂(1)₆](BF₄)₅ and [(CF₃SO₃)₈⊂Ag₁₂(1)₆](CF₃SO₃)₄ from the calix[4]resorcinarene-based tetrakisimidazolium salts H₄-1(X)₄ and Ag^I ions employing the metal-carbene directed self-assembly and hierarchical template strategies. An [Ag(CH₃CH)₄(BF₄)₈]^7- anion or Angewandte Chemie (International ed. in English)Hierarchical, Template-Controlled Self-Assembly of Two Different Organometallic Capsules from a Tetrakisimidazolium Salt.PMC127591952202510722JHZ003Li YHahn FEZhang LChang XTYuan GHan YFfalseHierarchical, Template-Controlled Self-Assembly of Two Different Organometallic Capsules from a Tetrakisimidazolium Salt.Controlling the assembly of molecular nanocapsules through metal-carbon bonds constitutes a major challenge in the field of supramolecular organometallic chemistry. Here, we demonstrate the construction of two nanosized dodecanuclear organometallic capsules, [{Ag(CH₃CN)₄(BF₄)₈}⊂Ag₁₂(1)₆](BF₄)₅ and [(CF₃SO₃)₈⊂Ag₁₂(1)₆](CF₃SO₃)₄ from the calix[4]resorcinarene-based tetrakisimidazolium salts H₄-1(X)₄ and Ag^I ions employing the metal-carbene directed self-assembly and hierarchical template strategies. An [Ag(CH₃CH)₄(BF₄)₈]^7- anion or 2026-01-01T00:00:00Z2026 Jan2026-06-06T09:37:40.363Z2026-05-28T03:12:17.515ZS-EPMC127591954123104410.1002/anie.202520814