{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"submitter":["Khalsa A"],"pubmed_abstract":["Study DesignRetrospective cohort study.ObjectivesPostoperative surgical site infections (SSI) remain a major cause of morbidity and cost in spine surgery. Existing risk calculators have limited applicability in this population. This study introduces a literature-informed, point-based SSI calculator designed to complement standard preoperative assessment. GPT-4 (OpenAI, San Francisco, CA) was used solely for structured literature synthesis and preliminary variable weighting.MethodsAdult patients undergoing spine surgery at a single academic center (2019-2025) were retrospectively reviewed. A 29-variable AI-assisted risk calculator integrating demographic, clinical, laboratory, and surgical factors was developed. SSI was defined using CDC/NHSN criteria with a 90-day window. Risk calculator p"],"journal":["Global spine journal"],"pagination":["21925682251415176"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12774816"],"repository":["biostudies-literature"],"pubmed_title":["AI-Assisted, Literature-Informed Development and Retrospective Validation of a Point-Based Surgical Site Infection Risk Calculator for Spine Surgery."],"pmcid":["PMC12774816"],"pubmed_authors":["Capone G","Kwon M","Assefa T","Peregoff J","Turlip RW","Zemberi J","Casper D","Hassan Z","Okorie N","Moser A","Khalsa A","Uzosike O","Cieplik NM"],"additional_accession":[]},"is_claimable":false,"name":"AI-Assisted, Literature-Informed Development and Retrospective Validation of a Point-Based Surgical Site Infection Risk Calculator for Spine Surgery.","description":"Study DesignRetrospective cohort study.ObjectivesPostoperative surgical site infections (SSI) remain a major cause of morbidity and cost in spine surgery. Existing risk calculators have limited applicability in this population. This study introduces a literature-informed, point-based SSI calculator designed to complement standard preoperative assessment. GPT-4 (OpenAI, San Francisco, CA) was used solely for structured literature synthesis and preliminary variable weighting.MethodsAdult patients undergoing spine surgery at a single academic center (2019-2025) were retrospectively reviewed. A 29-variable AI-assisted risk calculator integrating demographic, clinical, laboratory, and surgical factors was developed. SSI was defined using CDC/NHSN criteria with a 90-day window. Risk calculator p","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Jan","modification":"2026-06-06T13:04:14.783Z","creation":"2026-05-30T03:11:37.296Z"},"accession":"S-EPMC12774816","cross_references":{"pubmed":["41490806"],"doi":["10.1177/21925682251415176"]}}