biostudies-literatureFischer MJNational Institute of Diabetes and Digestive and Kidney DiseasesNIDDK NIH HHSNational Institutes of Health182-198.e1https://www.ebi.ac.uk/biostudies/studies/S-EPMC12776455biostudies-literatureUnknown87(2)<h4>Rationale & objective</h4>Adults receiving maintenance hemodialysis (HD) frequently report pain, yet detailed descriptions of pain in this population are lacking. This study examines pain locations, characteristics, and associations with other symptoms in adults receiving HD.<h4>Study design</h4>Cross-sectional analysis.<h4>Setting & participants</h4>Adults with moderate to severe chronic pain receiving maintenance HD enrolled in the multicenter HOPE Consortium Trial from 2021 to 2023.<h4>Exposure</h4>Sociodemographic, pain treatment, dialysis, medical comorbidity, and psychological and behavioral characteristics. Other patient-reported symptoms.<h4>Outcome</h4>Pain interference and severity as assessed by the Brief Pain Inventory (BPI) Interference and Severity subscales (range, 0-10)American journal of kidney diseases : the official journal of the National Kidney FoundationChronic Pain Locations, Characteristics, and Associations With Other Symptoms in Adults Receiving Maintenance Hemodialysis: Findings From the HOPE Consortium Trial.PMC12776455K26DK138374U01DK123814U01DK123813U01DK123812U01DK123821U01 DK123821U01DK123787U01 DK123787U01DK123786U01 DK123786U01 DK123814U01 DK123813U01 DK123812U01 DK123818U01DK123818U01 DK123817U01DK123817U01 DK123816U01DK123816K26 DK138374Kimmel PLPun PKeefe FJQamhiyeh RUnruh MLJhamb MJohansen KLEsserman DMehrotra RKalim SSchmidt RDember LMCharytan DMCukor DHsu JYFischer MJCavanaugh KLWalsh JNigwekar SDoorenbos AZYabes JGMorasco BJCrowley STScherer JSLockwood MBSteel JLfalseChronic Pain Locations, Characteristics, and Associations With Other Symptoms in Adults Receiving Maintenance Hemodialysis: Findings From the HOPE Consortium Trial.<h4>Rationale & objective</h4>Adults receiving maintenance hemodialysis (HD) frequently report pain, yet detailed descriptions of pain in this population are lacking. This study examines pain locations, characteristics, and associations with other symptoms in adults receiving HD.<h4>Study design</h4>Cross-sectional analysis.<h4>Setting & participants</h4>Adults with moderate to severe chronic pain receiving maintenance HD enrolled in the multicenter HOPE Consortium Trial from 2021 to 2023.<h4>Exposure</h4>Sociodemographic, pain treatment, dialysis, medical comorbidity, and psychological and behavioral characteristics. Other patient-reported symptoms.<h4>Outcome</h4>Pain interference and severity as assessed by the Brief Pain Inventory (BPI) Interference and Severity subscales (range, 0-10)2026-01-01T00:00:00Z2026 Feb2026-06-06T21:58:50.053Z2026-06-05T03:11:47.966ZS-EPMC127764554123816510.1053/j.ajkd.2025.09.009