{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Cvitkovic T"],"funding":["European Union's HORIZON 2020","European Union’s HORIZON 2020"],"pagination":["ivaf303"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12777964"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["41(1)"],"pubmed_abstract":["<h4>Objectives</h4>We sought to evaluate compliance and flow of the ascending aorta of patients with decellularized aortic homografts compared to donor age-matched healthy controls.<h4>Methods</h4>Male patients and donor age-matched male healthy controls were included. Cardiac function was evaluated by retrospectively electrocardiography-gated cine balanced steady-state free precession magnetic resonance imaging (MRI). Time-resolved 2- and 3-dimensional phase-contrast sequences were used to determine relative area change and pulse wave velocity as surrogate parameters for vessel compliance as well as maximum blood flow velocity.<h4>Results</h4>Thirteen patients were matched according to the age of their homograft donor (median 42 years, interquartile range [IQR] 32-50) to 7 healthy control"],"journal":["Interdisciplinary cardiovascular and thoracic surgery"],"pubmed_title":["Aortic Compliance After Root Replacement With Decellularized Homografts Versus in Donor Age-Matched Healthy Controls."],"pmcid":["PMC12777964"],"funding_grant_id":["643597"],"pubmed_authors":["Westhoff-Bleck M","Wacker F","Cvitkovic T","Beerbaum P","Tsimashok V","Horke A","Holst T","Czerner C","Gutberlet M","Avsar M","Ruhparwar A","Vogel-Claussen J","Petena E","Sarikouch S","Boethig D","Bobylev D","Beyer FH"],"additional_accession":[]},"is_claimable":false,"name":"Aortic Compliance After Root Replacement With Decellularized Homografts Versus in Donor Age-Matched Healthy Controls.","description":"<h4>Objectives</h4>We sought to evaluate compliance and flow of the ascending aorta of patients with decellularized aortic homografts compared to donor age-matched healthy controls.<h4>Methods</h4>Male patients and donor age-matched male healthy controls were included. Cardiac function was evaluated by retrospectively electrocardiography-gated cine balanced steady-state free precession magnetic resonance imaging (MRI). Time-resolved 2- and 3-dimensional phase-contrast sequences were used to determine relative area change and pulse wave velocity as surrogate parameters for vessel compliance as well as maximum blood flow velocity.<h4>Results</h4>Thirteen patients were matched according to the age of their homograft donor (median 42 years, interquartile range [IQR] 32-50) to 7 healthy control","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Jan","modification":"2026-06-06T21:58:48.818Z","creation":"2026-06-05T03:11:47.854Z"},"accession":"S-EPMC12777964","cross_references":{"pubmed":["41467751"],"doi":["10.1093/icvts/ivaf303"]}}