biostudies-literatureCvitkovic TEuropean Union's HORIZON 2020European Union’s HORIZON 2020ivaf303https://www.ebi.ac.uk/biostudies/studies/S-EPMC12777964biostudies-literatureUnknown41(1)<h4>Objectives</h4>We sought to evaluate compliance and flow of the ascending aorta of patients with decellularized aortic homografts compared to donor age-matched healthy controls.<h4>Methods</h4>Male patients and donor age-matched male healthy controls were included. Cardiac function was evaluated by retrospectively electrocardiography-gated cine balanced steady-state free precession magnetic resonance imaging (MRI). Time-resolved 2- and 3-dimensional phase-contrast sequences were used to determine relative area change and pulse wave velocity as surrogate parameters for vessel compliance as well as maximum blood flow velocity.<h4>Results</h4>Thirteen patients were matched according to the age of their homograft donor (median 42 years, interquartile range [IQR] 32-50) to 7 healthy controlInterdisciplinary cardiovascular and thoracic surgeryAortic Compliance After Root Replacement With Decellularized Homografts Versus in Donor Age-Matched Healthy Controls.PMC12777964643597Westhoff-Bleck MWacker FCvitkovic TBeerbaum PTsimashok VHorke AHolst TCzerner CGutberlet MAvsar MRuhparwar AVogel-Claussen JPetena ESarikouch SBoethig DBobylev DBeyer FHfalseAortic Compliance After Root Replacement With Decellularized Homografts Versus in Donor Age-Matched Healthy Controls.<h4>Objectives</h4>We sought to evaluate compliance and flow of the ascending aorta of patients with decellularized aortic homografts compared to donor age-matched healthy controls.<h4>Methods</h4>Male patients and donor age-matched male healthy controls were included. Cardiac function was evaluated by retrospectively electrocardiography-gated cine balanced steady-state free precession magnetic resonance imaging (MRI). Time-resolved 2- and 3-dimensional phase-contrast sequences were used to determine relative area change and pulse wave velocity as surrogate parameters for vessel compliance as well as maximum blood flow velocity.<h4>Results</h4>Thirteen patients were matched according to the age of their homograft donor (median 42 years, interquartile range [IQR] 32-50) to 7 healthy control2026-01-01T00:00:00Z2026 Jan2026-06-06T21:58:48.818Z2026-06-05T03:11:47.854ZS-EPMC127779644146775110.1093/icvts/ivaf303