biostudies-literatureUnknown13(1)Stanford GE<h4>Introduction</h4>Yoga is an emerging exercise choice for people with cystic fibrosis (CF), but evidence of its effect in this population is scarce, with a recent systematic review advocating for further research. Yoga Outcomes Get Assessed in CF (YOGA-CF) is a real-world multicentre randomised controlled trial (RCT) investigating a bespoke CF-specific online 12-week yoga intervention, vers usual care, to determine effectiveness for adults with CF.<h4>Methods and analysis</h4>A multicentre RCT of adults with CF across the UK. Participants are randomised to usual care or a 12-week online bespoke yoga programme with an expectation of two classes completed weekly. Assessments of lung function, 1 min sit-to-stand, the Cystic Fibrosis Questionnaire-Revised BMJ open respiratory researche003405https://www.ebi.ac.uk/biostudies/studies/S-EPMC12778263biostudies-literatureYoga Outcomes Get Assessed in Cystic Fibrosis (YOGA-CF): protocol of a multicentre interventional randomised controlled clinical trial-investigating effects of a 12-week yoga intervention for adults with cystic fibrosis.PMC12778263Stanford GECameron RAScarborough PCharman SCWagner APSimmonds NJfalseYoga Outcomes Get Assessed in Cystic Fibrosis (YOGA-CF): protocol of a multicentre interventional randomised controlled clinical trial-investigating effects of a 12-week yoga intervention for adults with cystic fibrosis.<h4>Introduction</h4>Yoga is an emerging exercise choice for people with cystic fibrosis (CF), but evidence of its effect in this population is scarce, with a recent systematic review advocating for further research. Yoga Outcomes Get Assessed in CF (YOGA-CF) is a real-world multicentre randomised controlled trial (RCT) investigating a bespoke CF-specific online 12-week yoga intervention, vers usual care, to determine effectiveness for adults with CF.<h4>Methods and analysis</h4>A multicentre RCT of adults with CF across the UK. Participants are randomised to usual care or a 12-week online bespoke yoga programme with an expectation of two classes completed weekly. Assessments of lung function, 1 min sit-to-stand, the Cystic Fibrosis Questionnaire-Revised 2026-01-01T00:00:00Z2026 Jan2026-06-06T12:35:52.83Z2026-05-30T03:11:11.676ZS-EPMC127782634149470010.1136/bmjresp-2025-003405