biostudies-literatureUnknown4(1)Czap AL<h4>Background</h4>The impact of mobile stroke units (MSUs) on outcomes in patients with large vessel occlusions eligible for endovascular thrombectomy (EVT) has yet to be characterized.<h4>Methods</h4>We completed a prespecified substudy of patients with EVT-eligible stroke with anterior and posterior circulation large vessel occlusions on computed tomography and/or computed tomography angiography who were enrolled in BEST-MSU (Benefits of Stroke Treatment using a Mobile Stroke Unit). Primary outcome was 90-day utility-weighted modified Rankin scale. Groups were compared using chi-square or Fisher's exact tests for categorical variables, and 2-sample <i>t</i>-tests for continuous variables. Multiple logistic regression was used to assess the effect of MSU on binary outcomes after adjustinStroke (Hoboken, N.J.)e001095https://www.ebi.ac.uk/biostudies/studies/S-EPMC12778464biostudies-literatureImpact of Mobile Stroke Units on Patients With Large Vessel Occlusion Acute Ischemic Stroke: A Prespecified BEST-MSU Substudy.PMC12778464Mackey JAlexandrov AWNavi BBLerario MPParker SAAlexandrov AVBowry RGonzalez MONour MGrotta JCTariq MBWang MSpokoyny ISingh NJacob APCzap ALYamal JMRajan SSJones WJfalseImpact of Mobile Stroke Units on Patients With Large Vessel Occlusion Acute Ischemic Stroke: A Prespecified BEST-MSU Substudy.<h4>Background</h4>The impact of mobile stroke units (MSUs) on outcomes in patients with large vessel occlusions eligible for endovascular thrombectomy (EVT) has yet to be characterized.<h4>Methods</h4>We completed a prespecified substudy of patients with EVT-eligible stroke with anterior and posterior circulation large vessel occlusions on computed tomography and/or computed tomography angiography who were enrolled in BEST-MSU (Benefits of Stroke Treatment using a Mobile Stroke Unit). Primary outcome was 90-day utility-weighted modified Rankin scale. Groups were compared using chi-square or Fisher's exact tests for categorical variables, and 2-sample <i>t</i>-tests for continuous variables. Multiple logistic regression was used to assess the effect of MSU on binary outcomes after adjustin2024-01-01T00:00:00Z2024 Jan2026-07-15T11:22:33.467Z2026-07-04T03:12:16.211ZS-EPMC127784644158604910.1161/SVIN.123.001095