biostudies-literatureUnknown76(1)Yamamoto EJapan Agency for Medical Research and DevelopmentThe obligately anaerobic, Gram-stain-positive coccobacilli strains OB7620<sup>T</sup> and OB7656<sup>T</sup> were isolated from faecal samples of healthy Japanese volunteers. Strain OB7620<sup>T</sup> showed the highest 16S rRNA gene sequence similarity to <i>Coprococcus comes</i> ATCC 27758<sup>T</sup> (98.4%) and <i>Clostridium nexile</i> DSM 1787<sup>T</sup> (96.3%). Strain OB7656<sup>T</sup> showed the highest 16S rRNA gene sequence similarity to '<i>Gluceribacter canis</i>' NATH-2371<sup>T</sup> (97.7%), <i>C. nexile</i> DSM 1787<sup>T</sup> (94.8%) and <i>Faecalimonas umbilicata</i> EGH7<sup>T</sup> (94.8%). These findings indicate that the two strains represent novel species. Genomic analysis clarified the phylogenetic relationship of <i>C. comes</i> with the species cluster designaInternational journal of systematic and evolutionary microbiologyhttps://www.ebi.ac.uk/biostudies/studies/S-EPMC12778736biostudies-literatureProposal of two novel species, <i>Allocoprococcus similis</i> gen. nov., sp. nov. and <i>Faecalimonas hominis</i> sp. nov., isolated from human faeces and genome-based reorganization of the genus <i>Coprococcus</i>.PMC12778736JP24ae0121035Sakamoto MMiwa KTsuchihashi HSakurai NHisatomi AYamamoto EOhkuma MKoizumi AfalseProposal of two novel species, <i>Allocoprococcus similis</i> gen. nov., sp. nov. and <i>Faecalimonas hominis</i> sp. nov., isolated from human faeces and genome-based reorganization of the genus <i>Coprococcus</i>.The obligately anaerobic, Gram-stain-positive coccobacilli strains OB7620<sup>T</sup> and OB7656<sup>T</sup> were isolated from faecal samples of healthy Japanese volunteers. Strain OB7620<sup>T</sup> showed the highest 16S rRNA gene sequence similarity to <i>Coprococcus comes</i> ATCC 27758<sup>T</sup> (98.4%) and <i>Clostridium nexile</i> DSM 1787<sup>T</sup> (96.3%). Strain OB7656<sup>T</sup> showed the highest 16S rRNA gene sequence similarity to '<i>Gluceribacter canis</i>' NATH-2371<sup>T</sup> (97.7%), <i>C. nexile</i> DSM 1787<sup>T</sup> (94.8%) and <i>Faecalimonas umbilicata</i> EGH7<sup>T</sup> (94.8%). These findings indicate that the two strains represent novel species. Genomic analysis clarified the phylogenetic relationship of <i>C. comes</i> with the species cluster designa2026-01-01T00:00:00Z2026 Jan2026-06-06T19:58:04.033Z2026-06-04T03:12:04.501ZS-EPMC127787364149877610.1099/ijsem.0.007011