{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["10(48)"],"submitter":["B de Abreu C"],"pubmed_abstract":["In the present study, we describe the toxicity mechanism of nickel tungstate nanoparticles (NiWO<sub>4</sub> NPs) and present experimental and computational advancements achieved through a combined approach to evaluate the toxicity of this semiconductor in the freshwater aquatic organism <i>Ceriodaphnia silvestrii</i> (Cladocera). Results from the acute toxicity test indicated that NiWO<sub>4</sub> induced immobility in <i>C. silvestrii</i> at concentrations exceeding 40 mg L<sup>-1</sup> (Dunn's test, <i>p</i> < 0.05). The 48-h EC<sub>50</sub> was 33.76 mg L<sup>-1</sup> ± 5.67. The sublethal concentrations of NiWO<sub>4</sub>, at 20 and 25 mg L<sup>-1</sup>, significantly decreased the ingestion rates of <i>C. silvestrii</i> (Dunnett's test, <i>p</i> < 0.05), directly affecting cladocera"],"journal":["ACS omega"],"pagination":["59413-59424"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12784302"],"repository":["biostudies-literature"],"pubmed_title":["Elucidating the Toxic Mechanism of NiWO&lt;sub&gt;4&lt;/sub&gt; to a Neotropical Microcrustacean: Experimental and Theoretical Insights."],"pmcid":["PMC12784302"],"pubmed_authors":["Mansano ADS","Assis M","Dorini TT","Virtuoso LS","Rocha GS","San-Miguel MA","Melao MDGG","Pereira TM","Gebara RC","Longo E","B de Abreu C"],"additional_accession":[]},"is_claimable":false,"name":"Elucidating the Toxic Mechanism of NiWO&lt;sub&gt;4&lt;/sub&gt; to a Neotropical Microcrustacean: Experimental and Theoretical Insights.","description":"In the present study, we describe the toxicity mechanism of nickel tungstate nanoparticles (NiWO<sub>4</sub> NPs) and present experimental and computational advancements achieved through a combined approach to evaluate the toxicity of this semiconductor in the freshwater aquatic organism <i>Ceriodaphnia silvestrii</i> (Cladocera). Results from the acute toxicity test indicated that NiWO<sub>4</sub> induced immobility in <i>C. silvestrii</i> at concentrations exceeding 40 mg L<sup>-1</sup> (Dunn's test, <i>p</i> < 0.05). The 48-h EC<sub>50</sub> was 33.76 mg L<sup>-1</sup> ± 5.67. The sublethal concentrations of NiWO<sub>4</sub>, at 20 and 25 mg L<sup>-1</sup>, significantly decreased the ingestion rates of <i>C. silvestrii</i> (Dunnett's test, <i>p</i> < 0.05), directly affecting cladocera","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Dec","modification":"2026-06-06T13:14:48.139Z","creation":"2026-05-30T03:11:35.362Z"},"accession":"S-EPMC12784302","cross_references":{"pubmed":["41522730"],"doi":["10.1021/acsomega.5c08907"]}}