{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Wei W"],"funding":["Key Project of Chongqing Special Program for Technological Innovation and Application Devel-opment","the \"Challenge System\" Project for Innovation and Breakthrough in the Seed Industry of Chong-qing Municipality: Coptis Chinen-sis ,the National Key Research and Development Program of China"],"pagination":["431"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12786017"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["27(1)"],"pubmed_abstract":["The basic leucine zipper (bZIP) transcription factors play crucial roles in plant growth and stress adaptation. However, a comprehensive genome-wide analysis of this family has been lacking in the medicinal plant <i>Coptis chinensis</i>. In this study, we identified 55 bZIP genes (<i>CcbZIPs</i>) from the <i>C. chinensis</i> genome and systematically classified them into 12 subfamilies through phylogenetic analysis with <i>Arabidopsis thaliana</i>. Notably, subfamilies L and O were absent, while two orphan genes were discovered, indicating lineage-specific evolution. Expression profiling revealed that numerous <i>CcbZIPs</i> respond dynamically to temperature and light stresses in a tissue-specific manner. These findings provide a foundation for understanding the regulatory roles of CcbZIP"],"journal":["International journal of molecular sciences"],"pubmed_title":["Genome-Wide Identification and Analysis of bZIP Transcription Factors in &lt;i&gt;Coptis chinensis&lt;/i&gt; Reveals Their Regulatory Roles in Stress Responses."],"pmcid":["PMC12786017"],"funding_grant_id":["CSTB2024TIAD-KPX0049","Grant No.2022YFD1201600"],"pubmed_authors":["Mo R","Guo L","Pan Y","Le Z","Wei W","Wang Y"],"additional_accession":[]},"is_claimable":false,"name":"Genome-Wide Identification and Analysis of bZIP Transcription Factors in &lt;i&gt;Coptis chinensis&lt;/i&gt; Reveals Their Regulatory Roles in Stress Responses.","description":"The basic leucine zipper (bZIP) transcription factors play crucial roles in plant growth and stress adaptation. However, a comprehensive genome-wide analysis of this family has been lacking in the medicinal plant <i>Coptis chinensis</i>. In this study, we identified 55 bZIP genes (<i>CcbZIPs</i>) from the <i>C. chinensis</i> genome and systematically classified them into 12 subfamilies through phylogenetic analysis with <i>Arabidopsis thaliana</i>. Notably, subfamilies L and O were absent, while two orphan genes were discovered, indicating lineage-specific evolution. Expression profiling revealed that numerous <i>CcbZIPs</i> respond dynamically to temperature and light stresses in a tissue-specific manner. These findings provide a foundation for understanding the regulatory roles of CcbZIP","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Dec","modification":"2026-06-30T03:26:38.534Z","creation":"2026-06-30T03:21:04.959Z"},"accession":"S-EPMC12786017","cross_references":{"pubmed":["41516304"],"doi":["10.3390/ijms27010431"]}}