{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Li M"],"funding":["National Key R&D Program of China","Guangdong Key Laboratory of Plant Adaptation and Molecular Design","Natural Science Foundation of Guangdong Province"],"pagination":["318"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12786271"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["27(1)"],"pubmed_abstract":["Anthocyanins, biosynthesized through the flavonoid pathway, critically determine floral coloration and ornamental value in plants. While floral development has been extensively studied in <i>Gerbera hybrida</i>, the microRNA-mediated regulation of anthocyanin biosynthesis remains unclear. In this study, we identified and characterized the precursor of gerbera microRNA156 (GhmiR156), which exhibits a typical stem-loop secondary structure. The mature GhmiR156 sequence shows 93.65% similarity with miR156 from other plants. Through target prediction analysis, we identified five potential target genes of GhmiR156, all encoding SQUAMOSA Promoter-Binding Protein-Like (SPL) transcription factors. Among these, the gene c35442.graph_c0, which shares the highest similarity with <i>AtSPL2</i> in Arabi"],"journal":["International journal of molecular sciences"],"pubmed_title":["GhmiR156-&lt;i&gt;GhSPL2&lt;/i&gt; Module Regulates Anthocyanin Biosynthesis of Ray Florets in &lt;i&gt;Gerbera hybrida&lt;/i&gt;."],"pmcid":["PMC12786271"],"funding_grant_id":["2023A1515012864","2022B1212010013-7","2018YFD1000404"],"pubmed_authors":["Luo Q","Shi S","Liao B","Chen Y","Wang X","Wang Y","Li M"],"additional_accession":[]},"is_claimable":false,"name":"GhmiR156-&lt;i&gt;GhSPL2&lt;/i&gt; Module Regulates Anthocyanin Biosynthesis of Ray Florets in &lt;i&gt;Gerbera hybrida&lt;/i&gt;.","description":"Anthocyanins, biosynthesized through the flavonoid pathway, critically determine floral coloration and ornamental value in plants. While floral development has been extensively studied in <i>Gerbera hybrida</i>, the microRNA-mediated regulation of anthocyanin biosynthesis remains unclear. In this study, we identified and characterized the precursor of gerbera microRNA156 (GhmiR156), which exhibits a typical stem-loop secondary structure. The mature GhmiR156 sequence shows 93.65% similarity with miR156 from other plants. Through target prediction analysis, we identified five potential target genes of GhmiR156, all encoding SQUAMOSA Promoter-Binding Protein-Like (SPL) transcription factors. Among these, the gene c35442.graph_c0, which shares the highest similarity with <i>AtSPL2</i> in Arabi","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Dec","modification":"2026-05-30T03:20:05.084Z","creation":"2026-05-30T03:11:37.391Z"},"accession":"S-EPMC12786271","cross_references":{"pubmed":["41516195"],"doi":["10.3390/ijms27010318"]}}