biostudies-literatureRathnayake NJapan Agency for Medical Research and Development17https://www.ebi.ac.uk/biostudies/studies/S-EPMC12797486biostudies-literatureUnknown22(1)<h4>Background</h4>Leptospirosis, caused by pathogenic Leptospira spp., is an important zoonotic disease that is found globally, with recent outbreaks posing a major public health challenge. This disease affects a wide range of mammalian species. While rodents, dogs, cattle, and buffaloes are recognized reservoirs of Leptospira, the role of swine in transmission in Sri Lanka remains unclear. This study aimed to investigate the carrier status of Leptospira spp. in swine raised for human consumption in Sri Lanka, and to assess potential zoonotic risks.<h4>Results</h4>Analysis of livestock data revealed the highest density of pigs in the Gampaha, Colombo, and Puttalam districts. Kidney (n = 181) and blood (n = 25) samples were collected from swine slaughtered for human consumption in the ColoBMC veterinary researchDetection of P1 and P2 Subclades of Leptospira carriage in swine in Sri Lanka.PMC12797486JP24fk0108683Rathnayake NMuthusinghe DBandara VShiokawa KYoshimatsu KGamage CKoizumi NVijeyakumaran RNalinda RSenarathne PSarathkumara YRajapakse SfalseDetection of P1 and P2 Subclades of Leptospira carriage in swine in Sri Lanka.<h4>Background</h4>Leptospirosis, caused by pathogenic Leptospira spp., is an important zoonotic disease that is found globally, with recent outbreaks posing a major public health challenge. This disease affects a wide range of mammalian species. While rodents, dogs, cattle, and buffaloes are recognized reservoirs of Leptospira, the role of swine in transmission in Sri Lanka remains unclear. This study aimed to investigate the carrier status of Leptospira spp. in swine raised for human consumption in Sri Lanka, and to assess potential zoonotic risks.<h4>Results</h4>Analysis of livestock data revealed the highest density of pigs in the Gampaha, Colombo, and Puttalam districts. Kidney (n = 181) and blood (n = 25) samples were collected from swine slaughtered for human consumption in the Colo2025-01-01T00:00:00Z2025 Dec2026-06-06T15:23:04.824Z2026-06-01T03:10:59.796ZS-EPMC127974864135115510.1186/s12917-025-05171-3