biostudies-literatureIwasaki Ythe Ministry of Health, Labor, and Welfare, Tokyo, Japan6https://www.ebi.ac.uk/biostudies/studies/S-EPMC12797702biostudies-literatureUnknown6(1)<h4>Background</h4>Volatile anesthetics have been suggested to exert neuroprotective effects in patients with subarachnoid hemorrhage caused by a ruptured cerebral aneurysm. However, their effects on functional outcomes remain unverified. We assessed the association between volatile anesthetics and functional outcomes in patients with subarachnoid hemorrhage.<h4>Methods</h4>Using data from the Japanese Diagnosis Procedure Combination inpatient database, patients with subarachnoid hemorrhage, aged = 18 years, and undergoing any procedures for aneurysm treatment were selected. Patients were categorized into those who received volatile anesthetics and those who did not. The primary outcome was a composite of in-hospital death or impaired functional outcome at discharge. The secondary outcomesJournal of anesthesia, analgesia and critical careRelationship between volatile anesthetics and functional outcomes in patients with subarachnoid hemorrhage.PMC1279770220AA2005Imaizumi TKaiho YIkumi SFushimi KYamauchi MIwasaki YTarasawa KFujimori KYabuki SfalseRelationship between volatile anesthetics and functional outcomes in patients with subarachnoid hemorrhage.<h4>Background</h4>Volatile anesthetics have been suggested to exert neuroprotective effects in patients with subarachnoid hemorrhage caused by a ruptured cerebral aneurysm. However, their effects on functional outcomes remain unverified. We assessed the association between volatile anesthetics and functional outcomes in patients with subarachnoid hemorrhage.<h4>Methods</h4>Using data from the Japanese Diagnosis Procedure Combination inpatient database, patients with subarachnoid hemorrhage, aged = 18 years, and undergoing any procedures for aneurysm treatment were selected. Patients were categorized into those who received volatile anesthetics and those who did not. The primary outcome was a composite of in-hospital death or impaired functional outcome at discharge. The secondary outcomes2025-01-01T00:00:00Z2025 Dec2026-06-06T15:23:20.026Z2026-06-01T03:11:02.659ZS-EPMC127977024135075810.1186/s44158-025-00325-z