biostudies-literatureUnknown135(6)Jammer I<h4>Background</h4>Hypotension after major noncardiac surgery is associated with increased morbidity, mortality, and costs, and is often treated with postoperative vasopressor infusions. The frequency of administration in the postoperative period is unknown.<h4>Methods</h4>This international prospective cohort study was conducted between October 2020 and October 2023. At each hospital, adults undergoing noncardiac surgery were enrolled into two cohorts: all consecutive patients for 1 week (Cohort A) and an additional sample of up to 30 consecutive patients administered postoperative vasopressor infusions within 1 yr (Cohort B). The primary outcome (Cohort A) was the incidence of postoperative vasopressor infusions, defined as any continuous infusion of vasopressors. Secondary outcomes inclBritish journal of anaesthesia1609-1617https://www.ebi.ac.uk/biostudies/studies/S-EPMC12799376biostudies-literatureVasopressor use after noncardiac surgery: an international observational study.PMC12799376Wallon GKaraliunaite ZMarinho RHolsken OBill VHumphrey CStrzelecki AHaas ABuren LAHMorosanu BKirov MBrucker CRubio-Baines IIHebatullah RLittlejohns AFletcher PLiew SJudith PBhowmick KCastro LCGhmagh RSerdobintseva EValadkhani ARamirez LNavarro-Perez RSantos AEllie KShivarev AIbrahim Mohamed AMBartlett EBartlett LElbahnasy MCargill AAbdelwahab KBelarabi OHoward LAnagnostides PZabolotskikh ITemple NCurrigan DAnastasescu ETreskatsch SAkcil EFValarie MGerea AValero JDogan LWallqvist JNicoletti RBelkhadir ZPresti GDimitrovski AStojiljkovic DLRusu LWooldridge BHadi NBecherucci FTeresa BAlttir MBhatia KOrlova ESell ABlixt CMachin JYamashita KUchiyama MDebouche SBrunete TPrimozic KKVaron VTew ZYMcivor EHanley CTutino LNikonov AAlkseek ARiaz MSSazak HSharma AGogakos ALokar MVan Den Ende TConyers RPerez Rivera CJMontero-Lopez PReece-Anthony RWotton-Hamrioui KBroderick AHurin PRallis TRigaudy MCallaghan HCoe RRipolles JPhilipose KO'Reilly KEl-Hibri FSponholz CJohnson LAssimakopoulos JLeonova EMarkovic MPineda JHamid HKSMartinez RBeloeil HChannabasappa SClara Fong HLEwington IDean YERasmussen LSAbbas AFarcas EAbbas MSudevan MAjami SFarah ISyed NCunha RPKanakaraj MHerzberg MAl-Juaifari MAAbdelmotieleb MHaider SRanjan PAlshareea EMalanova AUroda KNicki RLizzie FShah MWeskamm LShah PSadullah JTurhan SCLundevall VSundaram VSamy APetrun AMPauling SAyotte SSreckovic SLo CHansen CHSala-Trull CMoonesinghe ROlsen RBIatrelli IPistiolas GKunst GMendes EVenter STutt GOglinda DBergmann LParini ABiju PAlhalabi WBartmanska MGotz VCreagh-Brown BGarcia-Miguel FJShaw DBonna MKleikamp BSinanovic IKroker AMirabella LStembergar SBJama RWriting committee for the Squeeze investigatorsThomas MSemenas EThomas WStachtari CShaw JLotz TChau ICarvelli PTharayil AGCrouton FDaamen STete XAl-Omary SBlack CGonzalez-Suarez SMarino CAlbadalejo ABArthur Teo WPFonseca IAlison IRichmond GAmada HAlison SGonzalez ABVester-Andersen MWolsted HEmara MMBesch GLockwood JKilsand KCatalisano GMichalak NCobilinschi CYazgec HGopal VJonsson CDes Deserts MDRamsami JMavroudi EGarcia-Mendez JPHubbard KRobu CVan Lier FPradella ABaines KFreeman DBalkhi HAr AYGomm EHegazi AMall AMuino-Palomar VVickers RNelly ESpikes KKartite NKapasouri EMGecele CWard LNair RChowdhury PJammer IKovacevic JOpalinska MPeter BGartner SSchenk JLazaro FGDeery JBracun LGomez-Gonzalez ERT-Michael HNick MDilmen OKDullenkopf AShemies MZani GBosamia HPerumbadage GStirrup SRajkovic MDas ACara-Gilabert CZolger DMcelroy BAbuleil ATrovisco SAlmahroush MJames JSameh SMbama WSameh MParsons PRusso ABalonov KKida TGuran CTHaji MShaikh NJosipovic MQuindoyos JChardon NGutierrez ACraig JKaya EKuroda KMasters PHowells PRitzema JGidiem DRosenau LMartinos CNtakoula ABolger AJenfa GPreckel BHerzog NZiemann SNovakovic BBarath BSilva FPapadakis EAl-Touny SPreedy COlesen CMDeniz EAMew LPazmino-Canizares JJones AGolden DTye LAl-Touny AKrogstad ERGontse LChew MWoodburn MNetherton KChoo LYDiekmann MColla JStojanovic MBlunt LGrußer LHorne ZCotae AMLushiku LTGuile LBouaoud STrposka AKavlak SAAhmed QTTreus ESklavou GAckerley AChesov IArora HBoselli EIlchev TKing-Koi BDemiroluk ODingle BXara DDorado CBElin BFagerlund MJDinesen FSevdi MSFiouni SRamanathan LPaul ACDiez YMUgool MBillmann MDe Souza Neto EPManjooran GAvidzba AMateu Campos MLParfrey TFoss NBVetrugno LAbid SFrancis OPriestly VBubenek-Turtoni SLindsay CAkbari AAScott ZStranger ESpeziale CYeung JHuf RAbidin HZRavn MCCardoso FGurnee AAshok SCollins KMonib FSchick BSanga DMChetty STerenzoni MWilson KStrandberg ERichard PGoranovic THodson KMoody AAna KPrydz ALucas RSubbotin VFilizoglu SAHayward LKaye AWelters IMurciego ACBensalem MDavies SParotto MShiner CMBellini VDavies JSorokos KJoseph EJClark TDavies CScheeren TWLSekulic AHazelton TValeanu LOakley NKlacar RWinslow LAmin ALundstrom LHEl Ahmadi BEkinci OPitts SMiroshnichenko MLuzon MKulikov AMeuret LVan Beest PAVilleneuve JPanagiotou EMattina GBaldisserotto GPalibrk IKlingler HBrookman SJensen LTFedunets DEfthymiou ARuiz AHighton DSchroder HDavey MZahra MSTsuro TVarodan ARHamdy OBhagyesh SKnutsen DFManeva GMogahed MAsaul LSanchez HVJoe SProbier ZBrandhorst PMogane PPerente MMarasinska KAHenrik RCaldeiro JGranja CWindsor KOrasanu TZamidei LMajor AWilcock RWeston HSmit MSchening AKarpeikin VLam CMavani ZBignami EGIsmail ZHeather TGkiokas GElnoamany SChockalingam PRodriguez PKurahashi KHarding RTorrao CSoula EKarasu DVracevic DGeitmann TPrashant VThayaparan SHaugstvedt AFReuter DRose CAkintunde AWhitehouse TElsawy SOmar SCFreigofer MMansour EKumar ADias LKhomenko OMax HPilson KHassan MHKnotzer JShrivathsa AMciver WBaxter-Dore SBrandsborg BStromgaard Andersen MAConsales GAbodun MRauf JCucchiara TCNovak JReimers SWegge MAl-Awwady ANGarci ECDe Pretto RAspa PMaria FMiller MAstrakov SErkalp KWaugh VRudrappa SPLazopoulos ADourado CLopez MWong BBalakrishnan KPoonawala HDe Keijzer INOzgunay SEMullhi ROven VSayan ASamah SRNewton RJemmett KClaudette JPalma SAbdelrouf Ibrahim WBraviner JThornely EKarkala EIppolito MSimmers NVeelo DPPirovano FFlick MIkenga SChevalier SSante LIngall EDolinar JReed BJames Bannerman MRIdarraga STooze JSaint BHassan RKoch CMeirau EMahecic TTElgendy HCarter HDaubenfeld TDavis JHilton JKromberg LSAbdulwahed EHasani ANeto RElhadi MMickle PLukachan GAGuarnera MDe Waal EECPassos RGuerci PRomano BMarch SDmytriiev DJeyabraba SSeaman RFricano DCTeja BFlavell EPetersen LArcoria DLara LAFleming NTsang TMAlagoz ACorga RTunali YVyas MHell LDucrocq NEgilsson HBeranova ESarcevic AGoncalves NWutte WTulloch ACihoric MLara MAPye AMoutlana HMartinetti NYvonne BAlfonso JSigurdardottir AGarcia Sanchez AMWhitehead VSampaio JMclintock GTheodoraki KOvung RGregory TSigmundsson TSHarris FArias AHarris JAhmed SRosendahl AWaddell GSinclair JAhmed KLorinda EAhmed EVerula JDelgado DStagg CRemedios ENicholas KSahin ASPearcey SJozic JFarrar ABaldwin MGiles JAbdelrahman EGhannam ASchmid SVan Haeringen STavares MFasham JRose BOWilce AOhnstad HMMorenikeji AAskar OHumphreys SPelletier CMathai ASJooma ZCascarano LBonetti ABorle AFingler GSzewczyk MPassariello EAslanidis TMorimatsu HKhaity APope RHassan SKNorris MLassola SMoura PKnight AWilliams SAAries PCrasta SJohnsen RStewart RAnthony TSaric JPGreco MKaplan ADe'Ath YDingezweni SRoberts MMckie HBouhemad BPriani PMackay HForni LSvendsen CNSchmidt GBascombe CZore WOzalp ATanas YShearer LMckernan TDow OTrivedi MMiln RDrobnjak BSawyerr AKamundi CKoglberger PJamieson JMarson GDe Boer HDSuvorin PSinanan NNielsen BOGuclu CYYao AHaugerud ABurak MReschreiter HRaimundo AAlexander PDabrowska DChitnis STodorova DSaad MBarrett KMilan ZSolly RWickramasinghe MMeeks DSmith ASmith HLawrence MRaveau GTruman NPerry CCappellini INaili ASmith TTena SAKumari VBacer BFagerberg SKAsmaa HAndersen KMMoise ALowes ABalescu CFurman MWilliams KWilliams JPatlola PBouchenak KGranstrom ABradbeer SZaharenkova JPatel SMahdy MRossaint RVokuhl CBurr JFanny BMirea LSloan BChakane PMPaas IJELukasz KIzmailov IHansson MSaada HGarcia CDHusebekk OURatcliffe AMazlan MZGibson CDjukanovic MMani NSaugel BSchjorring OLNaumovski FGlargaard GDjukanovic NPepe NGrintescu IMSteinmetz JRamadan DCarlota Canada MAGarvey VTorlinski TMostafa SAnger MServen MGSaverimuttu BDe Candia ACevik BEBuckley SKolsen-Petersen JASehlapelo MRand JLangridge ELeeson HBarbetakis NPereira DNeporada ELysak ESivanandan SGuinot PGBecerra-Bolanos ATrembach NKondili EAdam VNGarcia-Sanchez JIPereira JToner AMania AFarsi SEdmunds TJayaraman APopovic SEdarous AMeco BCAshby KBabu TBoleac DWyatt COsey CBrigid HMellor THabicher MBouquerel RManley REvans WAgius NFelloni GGurbuz HSander MWatkin DKuleshov OMonedero PJonikaite LCortegiani ALewis SLewis TBelagodu ZAmaral RSanna AAmaral LBakeer HBPoredos PMusa AKozul ILe Gaillard BSella MVirdee GBahri RRivas LNorberg APinzon LPKhanna PVidal CGiacomucci ARafiq KRamalingam BBoyer NSamara EHernanz-Rodriguez GEl Koundi AScarpone EZadiraca NMiranda LOliveira DLim JCecconi MRamsaran RGhafoor HLulic ISidiropoulou ELojna KTeema ELefevre MLuque-Pelaez MSigurdsson MINwalusi IHughes RWilkins HBensghir MSzymiczek KVithanage TMartin PFynn AKearney AMatthew BSolomon BFoulds AParish BSmid-Nanninga HDel Carmen Iribarren Mateos MHughes AEfremov SCosta ARFusari MToleska MGresty JMendonca JAnita RRamdan AOrhun GKim DElassall GLadha KRodriguez-Perez AAsgarpur GYigit YRodrigues JTRedondo PEscribano-Arranz ASaracoglu KTArencibia-Almeida APowell RMatias FPaliouras DKuzkov VMelody TCaunter SHigo OBrunelli FLotierzo MStamatis KNielsen MATakei TRamos HAdams LTiple MAllen KTanna SShipway TIngoglia GTonev DApostolidou SMerchant NSchneck ERadovan WHarlet PKazi AShephardson SSpadaro SKempe TKoopman SSZamudio DBhagavath K R AMinto GAbdelsalam MSangalang ATorregiani GNesreen TCanbaz MNielsen RPRahman NJack BArandel KPinto AWoodgate AEid AAbdelsakhi MDidriksson HOjeda-Betancor NGarrod EStenersen IKDorr KEl-Desoki Mahmoud EIBranney DHerman MDinesh YRogers LUngureanu RTripkovic MRothwell JSchazl TLebuffe GRicardo MRogers FMilenovic MMiori SVan Bruchem RSaidahmed EWunsch HMarinkovic OBondergaard MOlufuwa OKhoronenko VNguyen MHegermann HAlexopoulou PSchmitt JNikolic AKurnik GFord ASerralta FCampbell BGonzales JJobes LfalseVasopressor use after noncardiac surgery: an international observational study.<h4>Background</h4>Hypotension after major noncardiac surgery is associated with increased morbidity, mortality, and costs, and is often treated with postoperative vasopressor infusions. The frequency of administration in the postoperative period is unknown.<h4>Methods</h4>This international prospective cohort study was conducted between October 2020 and October 2023. At each hospital, adults undergoing noncardiac surgery were enrolled into two cohorts: all consecutive patients for 1 week (Cohort A) and an additional sample of up to 30 consecutive patients administered postoperative vasopressor infusions within 1 yr (Cohort B). The primary outcome (Cohort A) was the incidence of postoperative vasopressor infusions, defined as any continuous infusion of vasopressors. Secondary outcomes incl2025-01-01T00:00:00Z2025 Dec2026-06-09T05:36:17.813Z2026-06-09T03:07:50.287ZS-EPMC127993764079649210.1016/j.bja.2025.07.034