biostudies-literatureUnknown12Frias-Toral E<h4>Introduction</h4>Clinical and nutritional research in Latin America faces significant challenges that limit scientific development and evidence-based healthcare. Understanding these barriers is essential for developing effective strategies to enhance research capacity in the region. This study aimed to identify multilevel barriers to clinical and nutritional research in Latin America and compare them between countries of different socioeconomic levels.<h4>Methods</h4>A cross-sectional study was conducted with 327 healthcare professionals involved in clinical and nutritional research across Latin America. Data collection occurred via an online survey in which participants rated the importance of 16 potential barriers on a 3-point Likert scale. Analysis included descriptive statistics, cFrontiers in nutrition1599344https://www.ebi.ac.uk/biostudies/studies/S-EPMC12801517biostudies-literatureMultilevel barriers to clinical and nutritional research in Latin America: a socioeconomic comparative analysis.PMC12801517Carriel-Mancilla JFranco-Nunez RFrias-Toral ELarreategui Arosemena RReytor-Gonzalez CAngamarca-Iguago JCalvo Higuera ICagua-Ordonez JContreras GMaza Moscoso CSimancas-Racines ASimancas-Racines DRestrepo JfalseMultilevel barriers to clinical and nutritional research in Latin America: a socioeconomic comparative analysis.<h4>Introduction</h4>Clinical and nutritional research in Latin America faces significant challenges that limit scientific development and evidence-based healthcare. Understanding these barriers is essential for developing effective strategies to enhance research capacity in the region. This study aimed to identify multilevel barriers to clinical and nutritional research in Latin America and compare them between countries of different socioeconomic levels.<h4>Methods</h4>A cross-sectional study was conducted with 327 healthcare professionals involved in clinical and nutritional research across Latin America. Data collection occurred via an online survey in which participants rated the importance of 16 potential barriers on a 3-point Likert scale. Analysis included descriptive statistics, c2025-01-01T00:00:00Z20252026-06-06T15:15:09.715Z2026-06-01T03:10:44.604ZS-EPMC128015174154119610.3389/fnut.2025.1599344